Nishio S, Mizuno J, Barrow D L, Takei Y, Tindall G T
Department of Pathology (Neuropathology), Emory University School of Medicine, Atlanta, Georgia.
Neurosurgery. 1987 Sep;21(3):371-7. doi: 10.1227/00006123-198709000-00016.
Nine cases of pituitary tumors composed of mixed tissue elements of adenohypophysial adenoma and Rathke's cleft cyst are reported. All cases were associated with hyperprolactinemia and were managed by transsphenoidal adenomectomy with good results. The clinical and pathological features are presented, and embryological pathogenesis for the occurrence of this unique association is discussed in connection with the high incidence of immunoreactive S-100 protein cells identified in tumor tissues. Patients with this kind of pituitary tumor can be managed in the same fashion as patients with other types of pituitary adenoma.
本文报告了9例由腺垂体腺瘤和拉克氏裂囊肿混合组织成分构成的垂体肿瘤。所有病例均伴有高催乳素血症，并接受经蝶窦腺瘤切除术治疗，效果良好。文中呈现了临床和病理特征，并结合肿瘤组织中免疫反应性S-100蛋白细胞的高发生率，讨论了这种独特关联发生的胚胎学发病机制。这类垂体肿瘤患者的治疗方式与其他类型垂体腺瘤患者相同。
