Sanchez Sherald, Deck Alicia, Baskerville Neill Bruce, Chaiton Michael
Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Ontario Tobacco Research Unit, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
JMIR Res Protoc. 2023 Jan 27;12:e42956. doi: 10.2196/42956.
The use of e-cigarettes, or vaping, has increased exponentially in the past decade, particularly among youth. Emerging evidence indicates growing nicotine dependence among youth, revealing historically higher rates of dependence among current e-cigarette users compared to rates seen in earlier research. Despite the urgent need for youth vaping cessation interventions, there is limited knowledge about the process of vaping cessation, and few evidence-based interventions are available to young people seeking support. A notable literature review on vaping cessation resources for young people recommended technology-based interventions, such as smartphone apps and SMS text messaging services, as a promising area of vaping cessation research and intervention development.
The primary aim of our study is to determine the effectiveness of the Crush the Crave app in supporting vaping cessation among youth recruited to the intervention arm via comparison with an assessment-only control group. The primary hypothesis is that participants in the intervention group-those using Crush the Crave-will be more likely to be abstinent at the 6-month follow-up point than participants in the assessment-only control arm.
A 2-arm, single-blind, parallel randomized controlled trial will be conducted over 12 months. Study invitations will be sent to 600 youth (age: 16-18 years) and young adult (age: 19-29 years) e-cigarette users and randomized between an intervention arm, which will be using Crush the Crave (n=300), and an assessment-only control arm (n=300) in a 1:1 ratio. The primary hypothesis is that participants in the intervention group-those using Crush the Crave-will be more likely to be abstinent at the 6-month follow-up point.
Study recruitment began on March 4, 2022. Recruitment is anticipated to be completed in December 2022.
This protocol describes one of the first-ever randomized controlled trial studies to evaluate the effectiveness of an app-based intervention for supporting vaping cessation among youth aged 16 to 18 years and young adults aged 19 to 29 years. The findings from our trial will help increase our understanding of the process of vaping cessation among youth and provide evidence on the effectiveness of an app-based intervention in helping young people quit vaping. The trial results will also have implications in the development of current and future approaches to youth vaping cessation.
OSF Registries osf.io/hmd87; https://doi.org/10.17605/OSF.IO/HMD87.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/42956.
在过去十年中，电子烟的使用呈指数级增长，尤其是在年轻人中。新出现的证据表明，年轻人对尼古丁的依赖在增加，与早期研究相比，目前电子烟使用者的依赖率在历史上更高。尽管迫切需要针对年轻人戒烟的干预措施，但对于戒烟过程的了解有限，对于寻求支持的年轻人来说，几乎没有基于证据的干预措施。一项关于年轻人戒烟资源的重要文献综述推荐基于技术的干预措施，如智能手机应用程序和短信服务，作为戒烟研究和干预发展的一个有前景的领域。
我们研究的主要目的是通过与仅进行评估的对照组比较，确定“粉碎渴望”应用程序在支持招募到干预组的年轻人戒烟方面的有效性。主要假设是，干预组中使用“粉碎渴望”的参与者在6个月随访时比仅进行评估的对照组参与者更有可能戒烟。
将进行一项为期12个月的双臂、单盲、平行随机对照试验。将向600名年龄在16至18岁的青少年和19至29岁的年轻电子烟使用者发送研究邀请，并以1:1的比例随机分为干预组（n = 300），该组将使用“粉碎渴望”，和仅进行评估的对照组（n = 300）。主要假设是，干预组中使用“粉碎渴望”的参与者在6个月随访时更有可能戒烟。
研究招募于2022年3月4日开始。预计招募工作将于2022年12月完成。
本方案描述了有史以来第一项评估基于应用程序的干预措施对16至18岁青少年和19至29岁年轻人戒烟有效性的随机对照试验研究之一。我们试验的结果将有助于增加我们对年轻人戒烟过程的理解，并提供基于应用程序的干预措施在帮助年轻人戒烟方面有效性的证据。试验结果也将对当前和未来年轻人戒烟方法的发展产生影响。
OSF注册中心osf.io/hmd87；https://doi.org/10.17605/OSF.IO/HMD87。
国际注册报告标识符（IRRID）：DERR1-10.2196/42956。
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