Lee J Austin, Matulis Christina
Attending Physician, Indiana University Health, Southern Indiana Physicians, Bloomington, IN.
Instructor in Emergency Medicine, Yale School of Medicine; Medical Simulation Fellow, Yale Center for Medical Simulation, New Haven, CT.
R I Med J (2013). 2023 Feb 1;106(1):14-16.
House fires can lead to cyanide poisoning and an associated elevated serum lactate level. Because of delays in obtaining serum cyanide levels, clinical symptoms and serum lactate are often used to guide clinical decision making and antidote administration. However, as this case report identifies, lower levels of serum lactate may in fact correlate with higher levels of serum cyanide that could benefit from treatment with an antidote.
房屋火灾可导致氰化物中毒及血清乳酸水平相应升高。由于获取血清氰化物水平存在延迟,临床症状和血清乳酸常被用于指导临床决策及解毒剂的使用。然而,正如本病例报告所指出的,较低的血清乳酸水平实际上可能与较高的血清氰化物水平相关,而这些较高的血清氰化物水平可能会从解毒剂治疗中获益。