Matsumura A, Nose T, Yamada T, Homma K
Department of Neurosurgery, University of Tsukuba, Ibaraki, Japan.
Neurosurg Rev. 1987;10(1):53-6. doi: 10.1007/BF01780595.
The mechanisms causing unclear differentiation of ICH in the acute phase by MRI are discussed. The increase of the hemoglobin concentration in the hematoma, caused by loss of the plasma component directly after onset, is one of the reasons for the shortening of relaxation times. The clotting system is also responsible for this shortening. Thus, the hematoma reaches the same intensity as the brain in the acute stage. Although knowledge from our animal experiments, in vivo as well as in vitro, cannot be directly transferred to the human, such experiments are useful for the understanding of the pathomechanism influencing MR imaging.
本文讨论了MRI在急性期导致脑出血信号不明确的机制。发病后血浆成分直接丢失导致血肿内血红蛋白浓度升高，这是弛豫时间缩短的原因之一。凝血系统也导致了弛豫时间的缩短。因此，在急性期血肿与脑实质信号强度相同。虽然我们的动物实验（包括体内和体外实验）的知识不能直接应用于人体，但此类实验有助于理解影响磁共振成像的病理机制。
