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两胎剖宫产术后再次试产及阴道分娩的临床体会:来自资源有限环境下的队列研究。

Experience on trial of labor and vaginal delivery after two previous cesarean sections: A cohort study from a limited-resource setting.

机构信息

Department of Obstetrics and Gynecology, Panzi General Referral Hospital, Bukavu, The Democratic Republic of Congo.

Université Evangélique en Afrique (UEA), Bukavu, The Democratic Republic of Congo.

出版信息

Int J Gynaecol Obstet. 2023 Jul;162(1):266-272. doi: 10.1002/ijgo.14665. Epub 2023 Feb 21.

Abstract

OBJECTIVE

To determine the success rate of trial of labor after two cesarean sections (TOLA2C) in the low-resource setting of the Democratic Republic of Congo (DRC) and to describe factors associated with success and related complications.

METHODS

A prospective cohort study was conducted from 2015 to 2020 in a teaching hospital. Patients who underwent TOLA2C were followed across prenatal visits, onset of spontaneous labor, and delivery. Demographics and clinical characteristics were documented. Pearson and Fisher χ tests were used. Predictors of successful vaginal delivery were determined by logistic regression (P ˂ 0.05).

RESULTS

Among 532 patients, the success rate of TOLA2C was 405 (76.1%). Factors associated with success included birth spacing ≥24 months (adjOR: 2.02 ; 95% CI 1.14-3.56; P = 0.015), previous vaginal delivery (adjOR: 5.02; 95% CI 2.71-9.31; P ˂ 0.001), intercalated vaginal delivery (adjOR: 5.15; 95% CI 2.28-11.65; P ˂ 0.001), cervical dilation >6 cm (adjOR: 2.37; 95% CI 1.92-6.05; P = 0.031) and/or complete dilation on arrival in the delivery room (adjOR: 1.96; 95% CI 1.33-11.45; P = 0.047) and oxytocin stimulation (adjOR: 4.24; 95% CI 1.82-9.91; P ˂ 0.001). No association with hemorrhage, uterine rupture, transfer to neonatology, or maternal-neonatal deaths was observed.

CONCLUSIONS

TOLA2C is possible in a low-resource setting with a high success rate and low rates of complications. Patient selection and obstetrical team competency are required.

摘要

目的

在刚果民主共和国(DRC)资源匮乏的环境下,确定二次剖宫产术后试产(TOLA2C)的成功率,并描述与成功相关的因素及其相关并发症。

方法

2015 年至 2020 年期间,在一家教学医院进行了一项前瞻性队列研究。对接受 TOLA2C 的患者进行了产前检查、自发性临产和分娩的随访。记录人口统计学和临床特征。使用 Pearson 和 Fisher χ 检验。通过逻辑回归(P<0.05)确定阴道分娩成功的预测因素。

结果

在 532 名患者中,TOLA2C 的成功率为 405 例(76.1%)。与成功相关的因素包括产次间隔≥24 个月(调整后的优势比:2.02;95%置信区间 1.14-3.56;P=0.015)、经阴道分娩史(调整后的优势比:5.02;95%置信区间 2.71-9.31;P<0.001)、中间经阴道分娩(调整后的优势比:5.15;95%置信区间 2.28-11.65;P<0.001)、宫颈扩张>6cm(调整后的优势比:2.37;95%置信区间 1.92-6.05;P=0.031)和/或进入产房时完全扩张(调整后的优势比:1.96;95%置信区间 1.33-11.45;P=0.047)以及催产素刺激(调整后的优势比:4.24;95%置信区间 1.82-9.91;P<0.001)。未观察到与出血、子宫破裂、转新生儿科或母婴死亡相关的情况。

结论

在资源匮乏的环境下,TOLA2C 是可行的,成功率高,并发症发生率低。需要患者选择和产科团队的能力。

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