Department of Obstetrics and Gynecology, Panzi General Referral Hospital, Bukavu, The Democratic Republic of Congo.
Université Evangélique en Afrique (UEA), Bukavu, The Democratic Republic of Congo.
Int J Gynaecol Obstet. 2023 Jul;162(1):266-272. doi: 10.1002/ijgo.14665. Epub 2023 Feb 21.
To determine the success rate of trial of labor after two cesarean sections (TOLA2C) in the low-resource setting of the Democratic Republic of Congo (DRC) and to describe factors associated with success and related complications.
A prospective cohort study was conducted from 2015 to 2020 in a teaching hospital. Patients who underwent TOLA2C were followed across prenatal visits, onset of spontaneous labor, and delivery. Demographics and clinical characteristics were documented. Pearson and Fisher χ tests were used. Predictors of successful vaginal delivery were determined by logistic regression (P ˂ 0.05).
Among 532 patients, the success rate of TOLA2C was 405 (76.1%). Factors associated with success included birth spacing ≥24 months (adjOR: 2.02 ; 95% CI 1.14-3.56; P = 0.015), previous vaginal delivery (adjOR: 5.02; 95% CI 2.71-9.31; P ˂ 0.001), intercalated vaginal delivery (adjOR: 5.15; 95% CI 2.28-11.65; P ˂ 0.001), cervical dilation >6 cm (adjOR: 2.37; 95% CI 1.92-6.05; P = 0.031) and/or complete dilation on arrival in the delivery room (adjOR: 1.96; 95% CI 1.33-11.45; P = 0.047) and oxytocin stimulation (adjOR: 4.24; 95% CI 1.82-9.91; P ˂ 0.001). No association with hemorrhage, uterine rupture, transfer to neonatology, or maternal-neonatal deaths was observed.
TOLA2C is possible in a low-resource setting with a high success rate and low rates of complications. Patient selection and obstetrical team competency are required.
在刚果民主共和国(DRC)资源匮乏的环境下,确定二次剖宫产术后试产(TOLA2C)的成功率,并描述与成功相关的因素及其相关并发症。
2015 年至 2020 年期间,在一家教学医院进行了一项前瞻性队列研究。对接受 TOLA2C 的患者进行了产前检查、自发性临产和分娩的随访。记录人口统计学和临床特征。使用 Pearson 和 Fisher χ 检验。通过逻辑回归(P<0.05)确定阴道分娩成功的预测因素。
在 532 名患者中,TOLA2C 的成功率为 405 例(76.1%)。与成功相关的因素包括产次间隔≥24 个月(调整后的优势比:2.02;95%置信区间 1.14-3.56;P=0.015)、经阴道分娩史(调整后的优势比:5.02;95%置信区间 2.71-9.31;P<0.001)、中间经阴道分娩(调整后的优势比:5.15;95%置信区间 2.28-11.65;P<0.001)、宫颈扩张>6cm(调整后的优势比:2.37;95%置信区间 1.92-6.05;P=0.031)和/或进入产房时完全扩张(调整后的优势比:1.96;95%置信区间 1.33-11.45;P=0.047)以及催产素刺激(调整后的优势比:4.24;95%置信区间 1.82-9.91;P<0.001)。未观察到与出血、子宫破裂、转新生儿科或母婴死亡相关的情况。
在资源匮乏的环境下,TOLA2C 是可行的,成功率高,并发症发生率低。需要患者选择和产科团队的能力。