Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, CT.
Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA.
Am J Obstet Gynecol. 2019 Jan;220(1):98.e1-98.e14. doi: 10.1016/j.ajog.2018.09.034. Epub 2018 Sep 29.
Trial of labor after cesarean delivery is an effective and safe option for women without contraindications.
The objective of the study was to examine hospital variation in utilization and success of trial of labor after cesarean delivery and identify associated institutional characteristics and patient outcomes.
Using linked maternal and newborn hospital discharge records and birth certificate data in 2010-2012 from the state of California, we identified 146,185 term singleton mothers with 1 prior cesarean delivery and no congenital anomalies or clear contraindications for trial of labor at 249 hospitals. Risk-standardized utilization and success rates of trial of labor after cesarean delivery were estimated for each hospital after accounting for differences in patient case mix. Risk for severe maternal and newborn morbidities, as well as maternal and newborn length of stay, were compared between hospitals with high utilization and high success rates of trial of labor after cesarean delivery and other hospitals. Bivariate analysis was also conducted to examine the association of various institutional characteristics with hospitals' utilization and success rates of trial of labor after cesarean delivery.
In the overall sample, 12.5% of women delivered vaginally. After adjusting for patient clinical risk factors, utilization and success rates of trial of labor after cesarean delivery varied considerably across hospitals, with a median of 35.2% (10th to 90th percentile range: 10.2-67.1%) and 40.5% (10th to 90th percentile range: 8.5-81.1%), respectively. Risk-standardized utilization and success rates of trial of labor after cesarean delivery demonstrated an inverted U-shaped relationship such that low or excessively high use of trial of labor after cesarean delivery was associated with lower success rate. Compared with other births, those delivered at hospitals with above-the-median utilization and success rates of trial of labor after cesarean delivery had a higher risk for uterine rupture (adjusted risk ratio, 2.74, P < .001), severe newborn respiratory complications (adjusted risk ratio, 1.46, P < .001), and severe newborn neurological complications/trauma (adjusted risk ratio, 2.48, P < .001), but they had a lower risk for severe newborn infection (adjusted risk ratio, 0.80, P = .003) and overall severe unexpected newborn complications (adjusted risk ratio, 0.86, P < .001) as well as shorter length of stays (adjusted mean ratio, 0.948 for mothers and 0.924 for newborns, P < .001 for both). Teaching status, system affiliation, larger volume, higher neonatal care capacity, anesthesia availability, higher proportion of midwife-attended births, and lower proportion of Medicaid or uninsured patients were positively associated with both utilization and success of trial of labor after cesarean delivery. However, rural location and higher local malpractice insurance premium were negatively associated with the utilization of trial of labor after cesarean delivery, whereas for-profit ownership was associated with lower success rate.
Utilization and success rates of trial of labor after cesarean delivery varied considerably across hospitals. Strategies to promote vaginal birth should be tailored to hospital needs and characteristics (eg, increase availability of trial of labor after cesarean delivery at hospitals with low utilization rates while being more selective at hospitals with high utilization rates, and targeted support for lower capacity hospitals).
对于没有禁忌证的妇女来说,剖宫产术后试产是一种有效且安全的选择。
本研究旨在检查剖宫产术后试产的利用情况和成功率的医院差异,并确定相关的机构特征和患者结局。
利用 2010-2012 年加利福尼亚州产妇和新生儿医院出院记录和出生证明数据,我们在 249 家医院中确定了 146185 名足月单胎母亲,这些母亲有 1 次剖宫产史,且无先天性异常或明确的剖宫产禁忌证。在考虑患者病例组合差异后,为每家医院估计了剖宫产术后试产的风险标准化利用和成功率。比较高利用和高成功率的剖宫产术后试产医院与其他医院之间的严重产妇和新生儿发病率、产妇和新生儿住院时间的风险。还进行了单变量分析,以检查各种机构特征与医院剖宫产术后试产的利用和成功率的关系。
在总样本中,12.5%的妇女经阴道分娩。在调整了患者临床风险因素后,剖宫产术后试产的利用和成功率在医院之间差异很大,中位数分别为 35.2%(第 10 至 90 个百分位数范围:10.2-67.1%)和 40.5%(第 10 至 90 个百分位数范围:8.5-81.1%)。风险标准化的剖宫产术后试产的利用和成功率呈倒 U 形关系,即剖宫产术后试产的低利用或过度利用与较低的成功率相关。与其他分娩相比,在剖宫产术后试产利用率和成功率高于中位数的医院分娩的产妇,发生子宫破裂的风险更高(校正风险比,2.74,P<.001)、新生儿严重呼吸并发症的风险更高(校正风险比,1.46,P<.001)、新生儿严重神经并发症/创伤的风险更高(校正风险比,2.48,P<.001),但新生儿严重感染的风险更低(校正风险比,0.80,P=.003),以及严重新生儿意外并发症的风险更低(校正风险比,0.86,P<.001),并且产妇和新生儿的住院时间更短(校正平均比,母亲为 0.948,新生儿为 0.924,均 P<.001)。教学地位、系统隶属关系、更大的容量、更高的新生儿护理能力、麻醉可用性、更多的助产士分娩比例以及更少的医疗补助或无保险患者与剖宫产术后试产的利用和成功率呈正相关。然而,农村地区和更高的当地医疗事故保险保费与剖宫产术后试产的利用率呈负相关,而营利性所有权与较低的成功率相关。
剖宫产术后试产的利用和成功率在医院之间差异很大。促进阴道分娩的策略应根据医院的需求和特征进行定制(例如,增加低利用率医院的剖宫产术后试产的可用性,而在高利用率医院进行更有选择性的治疗,为容量较低的医院提供有针对性的支持)。