Brandstetter Maximilian, Brandstetter Andreas, Kainz-Schultes Sabine, Jacobs Volker R, Fazelnia Claudius, Fischer Thorsten, Bogner Gerhard
Department of Obstetrics and Gynecology, Paracelsus Medical University, Salzburg, Austria.
Department of Obstetrics and Gynecology, Sankt Josef Hospital, Vienna, Austria.
Geburtshilfe Frauenheilkd. 2025 Feb 7;85(8):862-869. doi: 10.1055/a-2513-6562. eCollection 2025 Aug.
The majority of obstetrical clinics do not offer a trial of labor after two Caesarean sections (TOLA2C) due to concerns about fetal and maternal complications such as uterine rupture or asphyxia. This study aimed to establish a delivery protocol for safely undergoing TOLA2C and analyzed predictors for a successful vaginal delivery.
Analysis of retrospectively collected data of all pregnant women after two consecutive Caesarean sections was performed at the Obstetrics Department of a tertiary community hospital from January 2013 until December 2022. Those who desired TOLA2C were screened by a senior obstetrician and had to consent to a delivery protocol consisting of five pre- and eight peripartum criteria. Maternal demographic data, indications for previous Caesarean sections and feto-maternal outcome parameters were compared between the successful TOLA2C group and the intrapartum Third-Caesarean section group.
In the study period, 385 women planned a delivery after two consecutive CS. Following the protocol, 358 patients (93.0%) were scheduled as elective repeat CS, while 27 (7.0%) attempted vaginal delivery. In this TOLA2C group, 17 women (63.0%) successfully delivered vaginally. In contrast, ten failed vaginal attempts (37.0%) resulted in nine intrapartum repeat CS and one intrapartum emergency CS. Women with prior vaginal delivery had a higher chance of a successful TOLA2C (p = 0.04). In comparison, women with a previous CS due to the indication of arrested labor had a higher risk for intrapartum repeat CS (p = 0.02). No fetal or maternal death occurred, and no major complications were observed.
Under the specified conditions, TOLA2C is safe for mother and fetus, and successful vaginal delivery is feasible.
由于担心胎儿和母亲出现诸如子宫破裂或窒息等并发症,大多数产科诊所不提供两次剖宫产术后试产(TOLA2C)。本研究旨在制定一项安全进行TOLA2C的分娩方案,并分析阴道分娩成功的预测因素。
对一家三级社区医院产科2013年1月至2022年12月期间连续两次剖宫产术后所有孕妇的回顾性收集数据进行分析。那些希望进行TOLA2C的孕妇由一位资深产科医生进行筛查,并且必须同意一项包括五项产前和八项产时标准的分娩方案。比较成功的TOLA2C组和产时第三次剖宫产组之间的产妇人口统计学数据、既往剖宫产指征以及母胎结局参数。
在研究期间,385名妇女计划在连续两次剖宫产术后分娩。按照方案,358例患者(93.0%)被安排进行择期再次剖宫产,而27例(7.0%)尝试阴道分娩。在这个TOLA2C组中,17名妇女(63.0%)成功阴道分娩。相比之下,10次阴道试产失败(37.0%)导致9例产时再次剖宫产和1例产时急诊剖宫产。既往有阴道分娩史的妇女成功进行TOLA2C的机会更高(p = 0.04)。相比之下,既往因产程停滞而行剖宫产的妇女产时再次剖宫产的风险更高(p = 0.02)。未发生胎儿或母亲死亡,也未观察到重大并发症。
在特定条件下,TOLA2C对母亲和胎儿是安全的,阴道分娩成功是可行的。