Department of Sexual Health & HIV Medicine, University Hospitals Sussex NHS Foundation Trust, Brighton BN2 5BE, UK.
Department of Sexual Health & HIV Medicine, University Hospitals Sussex NHS Foundation Trust, Brighton BN2 5BE, UK; and Brighton & Sussex Medical School, Brighton, UK.
Sex Health. 2023 Apr;20(2):177-179. doi: 10.1071/SH22192.
Event-based dosing (EBD) of HIV PrEP is as effective at preventing HIV transmission in MSM as daily dosing. There are limited data on the differences in STI testing frequency between MSM using EBD-PrEP and daily dosing. A total of 20% of 418 PrEP users were using EBD-PrEP and had a lower number of sexual partners (22 (27%) vs 142 (42%), P =0.008), tested for STIs less frequently (115 (18%) vs 69 (50%), P <0.001), but were diagnosed with a similar number of STIs ((35% vs 34%, P =0.54) compared to daily users. More research is needed to understand the optimal frequency for STI testing in MSM using EBD PrEP.
基于事件的艾滋病预防药物剂量调整（EBD）在男男性行为者（MSM）中的预防艾滋病效果与每日剂量相当。目前关于使用 EBD-PrEP 和每日剂量的 MSM 之间性传播感染（STI）检测频率差异的数据有限。在 418 名 PrEP 用户中，共有 20%的人使用 EBD-PrEP，他们的性伴侣数量较少（22 人（27%）与 142 人（42%），P=0.008），接受 STI 检测的频率较低（115 人（18%）与 69 人（50%），P<0.001），但诊断出的 STI 数量相似（35%与 34%，P=0.54）与每日使用者相比。需要进一步研究来了解 EBD PrEP 使用者的最佳 STI 检测频率。
