Burke G L, Voors A W, Shear C L, Webber L S, Smoak C G, Cresanta J L, Berenson G S
Department of Medicine, Louisiana State University Medical Center, New Orleans.
Pediatrics. 1987 Nov;80(5 Pt 2):784-8.
BP was measured in 440 children followed longitudinally from birth to 7 years of age in Bogalusa, LA. Levels, trends, and determinants of BP were evaluated in this newborn cohort. Both systolic and diastolic BP levels remained relatively constant between the ages of 6 months and 7 years. BP levels varied between the different instruments, and differences were also noted between measures obtained using the same instrument before and after venipuncture. White children were noted to have slightly higher levels of systolic and diastolic BP pressure at 6 months and 1 year of age, even after adjustment for body size. Significant prediction of year 7 BP rank occurred as early as 6 months of age for systolic and at 1 year of age for diastolic BP levels. Body size was inconsistently related to BP levels from ages 6 months through 4 years, but the relationship was stronger and more consistent with changes in body size. Of interest is the relatively constant levels of indirect BP during this period of rapid growth, as measured by currently available instruments. These data emphasize the importance of cardiovascular risk factor measurement during early life and of the need to improve methods of indirect BP measurement in infancy.
在路易斯安那州博加卢萨，对440名从出生到7岁进行纵向跟踪研究的儿童测量了血压。在这个新生儿队列中评估了血压水平、趋势和决定因素。收缩压和舒张压水平在6个月至7岁之间保持相对稳定。不同仪器测量的血压水平有所不同，在静脉穿刺前后使用同一仪器获得的测量值之间也存在差异。即使在调整了体型因素后，白人儿童在6个月和1岁时的收缩压和舒张压水平仍略高。早在6个月时收缩压以及1岁时舒张压水平就对7岁时的血压排名有显著预测作用。从6个月到4岁，体型与血压水平的关系并不一致，但这种关系在体型变化时更强且更一致。有趣的是，通过现有仪器测量，在这个快速生长时期间接血压水平相对稳定。这些数据强调了在生命早期测量心血管危险因素的重要性，以及改进婴儿期间接血压测量方法的必要性。
