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经导管主动脉瓣置换术使用 SAPIEN 3/Ultra 经导管心脏瓣膜-专家对手术规划和技术的共识。

Redo-Transcatheter Aortic Valve Implantation Using the SAPIEN 3/Ultra Transcatheter Heart Valves-Expert Consensus on Procedural Planning and Techniques.

机构信息

Thoracic, Vascular Sciences and Public Health, University of Padua Medical School, Padua, Italy.

Heart Institute, Hospital Universitari Germans Trias I Pujol, Barcelona, Spain.

出版信息

Am J Cardiol. 2023 Apr 1;192:228-244. doi: 10.1016/j.amjcard.2023.01.010. Epub 2023 Jan 27.

DOI:10.1016/j.amjcard.2023.01.010
PMID:36710143
Abstract

Recent guidelines on valvular heart disease in Europe and the United States have expanded the indications for transcatheter aortic valve implantation (TAVI) to younger patients and those at lower surgical risk with severe symptomatic aortic stenosis. Consequently, the number of TAVI procedures will significantly increase worldwide. Patients with longer life expectancies will outlive their transcatheter heart valves (THVs) and require established treatment strategies for re-intervention. Current data have shown encouraging outcomes, including low mortality, with redo-TAVI; in contrast, surgical explantation of THVs is associated with high mortality. Redo-TAVI, therefore, is likely to be the treatment of choice for THV failure. The expected increase in the number of redo-TAVIs stands in contrast to the current lack of evidence on how this procedure should be planned and performed, including the risks and pitfalls operators need to consider. Preliminary reports stress the importance of preprocedural planning, understanding of THV skirt and leaflet characteristics, and implantation guidelines specific to different THVs. Currently, SAPIEN 3/Ultra is the only THV approved in Europe and the United States for redo-TAVI. Therefore, we gathered a panel of experts in TAVI procedures with the aim of providing operative guidance on redo-TAVI, using the SAPIEN 3/Ultra THV. This consensus article presents a step-by-step approach encompassing clinical, anatomical, and technical aspects in preprocedural planning, procedural techniques, and postprocedural care. In conclusion, the recommendations aim to improve the feasibility, safety, and long-term outcomes of redo-TAVI, including the durability of implanted THVs.

摘要

最近在欧洲和美国发布的瓣膜性心脏病指南扩大了经导管主动脉瓣植入术(TAVI)的适应证范围,包括年龄较小和手术风险较低但有严重症状性主动脉瓣狭窄的患者。因此,全球范围内 TAVI 手术的数量将显著增加。具有更长预期寿命的患者将使用他们的经导管心脏瓣膜(THV),并需要制定针对再次介入的既定治疗策略。目前的数据显示,再次 TAVI 具有令人鼓舞的结果,包括较低的死亡率;相比之下,THV 的外科取出与高死亡率相关。因此,再次 TAVI 可能是 THV 失败的首选治疗方法。预计再次 TAVI 数量的增加与目前缺乏关于如何规划和执行该程序的证据形成鲜明对比,包括操作者需要考虑的风险和陷阱。初步报告强调了术前规划、理解 THV 裙边和瓣叶特征以及特定于不同 THV 的植入指南的重要性。目前,SAPIEN 3/Ultra 是唯一一种在欧洲和美国获准用于再次 TAVI 的 THV。因此,我们召集了 TAVI 手术方面的专家小组,旨在使用 SAPIEN 3/Ultra THV 提供再次 TAVI 的手术指导。本文提出了一个涵盖术前规划、手术技术和术后护理的临床、解剖和技术方面的逐步方法。总之,这些建议旨在提高再次 TAVI 的可行性、安全性和长期结果,包括植入 THV 的耐久性。

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