基于葫芦脲的荧光指示剂置换分析法用于检测有机化合物。
Cucurbit[]uril-based fluorescent indicator-displacement assays for sensing organic compounds.
作者信息
Duan Qunpeng, Chen Ran, Deng Su, Yang Cheng, Ji Xinxin, Qi Gege, Li Hui, Li Xiaohan, Chen Shihao, Lou Mengen, Lu Kui
机构信息
School of Chemical and Printing-Dyeing Engineering, Henan University of Engineering, Zhengzhou, China.
School of Chemical Engineering and Food Science, Zhengzhou Institute of Technology, Zhengzhou, China.
出版信息
Front Chem. 2023 Jan 13;11:1124705. doi: 10.3389/fchem.2023.1124705. eCollection 2023.
The widespread conversion of synthetic receptors into luminescent sensors has been achieved the use of fluorescent-indicator displacement assays (F-IDAs). Due to their rigid structures and efficient binding affinities, cucurbit[]urils, combined with a variety of fluorescent guests, have gained extensive utilization in fluorescent-indicator displacement assays for sensing non-fluorescent or weakly fluorescent organic compounds (analytes) in a selective and specific manner. This mini-review summarizes recent advances in the design of cucurbit[]uril-based fluorescent-indicator displacement assays and discusses the current challenges and future prospects in this area.
通过使用荧光指示剂置换分析法（F-IDAs），已实现将合成受体广泛转化为发光传感器。由于其刚性结构和高效的结合亲和力，葫芦[n]脲与多种荧光客体结合，已在荧光指示剂置换分析法中得到广泛应用，以选择性和特异性地检测非荧光或弱荧光有机化合物（分析物）。本综述总结了基于葫芦[n]脲的荧光指示剂置换分析法设计的最新进展，并讨论了该领域当前的挑战和未来前景。
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