Duan Qunpeng, Wang Fei, Lu Kui
School of Chemical and Printing-Dyeing Engineering, Henan University of Engineering, Zhengzhou, China.
School of Chemical Engineering and Food Science, Zhengzhou Institute of Technology, Zhengzhou, China.
Front Chem. 2022 Jul 18;10:973313. doi: 10.3389/fchem.2022.973313. eCollection 2022.
Macrocyclic arenes-based fluorescent indicator displacement assays (F-IDAs) offer a unique and innovative approach to chemosensing, taking molecular recognition in host-guest chemistry to a higher level. Because of their special architecture and versatile host-guest binding properties, macrocyclic arenes, principally calix[]arenes and, in recent years, pillar[]arenes, in combination with various fluorophores, are widely used in F-IDAs for the specific and selective sensing of cationic, anionic, and neutral analytes. In this paper, we review recent progress in the development of F-IDAs based on macrocyclic arenes and outline the prospects and remaining challenges relating to macrocyclic arenes-based F-IDAs.
基于大环芳烃的荧光指示剂置换分析（F-IDAs）为化学传感提供了一种独特且创新的方法，将主客体化学中的分子识别提升到了一个更高的水平。由于其特殊的结构和多样的主客体结合特性，大环芳烃，主要是杯芳烃以及近年来的柱芳烃，与各种荧光团相结合，被广泛应用于F-IDAs中，用于对阳离子、阴离子和中性分析物进行特异性和选择性传感。在本文中，我们综述了基于大环芳烃的F-IDAs开发的最新进展，并概述了与基于大环芳烃的F-IDAs相关的前景和尚存的挑战。
