Virology Department, Instiut Pasteur de Dakar, Dakar, Senegal.
Front Public Health. 2023 Jan 12;10:1060678. doi: 10.3389/fpubh.2022.1060678. eCollection 2022.
Monkeypox is a viral disease endemic to some countries in Central and Western Africa. However, sporadic human cases have also been reported outside of Africa. The first human case was reported in 1970 in the Democratic Republic of Congo. Very similar to the eradicated smallpox regarding its clinical representation, the Monkeypox disease is most common in children aged between 5 and 9 years with a fatality rate ranging from 1 to 11% in Africa. During the past decade, the number of countries that reported human cases of the disease grew significantly, while experts still sought knowledge on the characteristics of the virus. The recent increase in Monkeypox cases in many countries raises the concern about a possible global health threat. There is a need to subsequently provide insights into the incidence of Monkeypox disease and come up with mechanisms to prevent its emergence and contain its spread. Furthermore, it is crucial to have a better view of the global diagnostic capacity of the Monkeypox virus. This review aims to assess useful public health countermeasures to control the current multicountry outbreak of Monkeypox disease. Articles were searched in PubMed and Google Scholar electronic databases on 30 June 2022, using selected keywords, without language and date restriction. A total of 44 scientific records were published between 1 January 1962 and 30 June 2022. Herein, we discuss the epidemiological and public health situation at a global scale, provide an updated overview and data of utility for a better understanding of knowledge and research gaps in the epidemiology of the Monkeypox disease, and give useful measures for controlling the current multicountry outbreak.
猴痘是一种病毒病,流行于中非和西非的一些国家。然而,非洲以外也有散发病例报告。首例人类病例于 1970 年在刚果民主共和国报告。猴痘与已根除的天花在临床表现上非常相似,在非洲,该病最常见于 5 至 9 岁的儿童,死亡率在 1%至 11%之间。在过去十年中,报告人类猴痘病例的国家数量显著增加,而专家仍在寻求有关该病毒特征的知识。最近许多国家猴痘病例的增加引起了人们对可能出现的全球健康威胁的关注。因此,有必要深入了解猴痘病的发病率,并制定预防其出现和控制其传播的机制。此外,更好地了解全球猴痘病毒的诊断能力至关重要。本综述旨在评估控制当前多国猴痘病爆发的有用公共卫生对策。2022 年 6 月 30 日,在 PubMed 和 Google Scholar 电子数据库中使用选定的关键词进行了搜索,没有语言和日期限制。总共发表了 44 篇科学记录,发表日期为 1962 年 1 月 1 日至 2022 年 6 月 30 日。在此,我们讨论了全球范围内的流行病学和公共卫生状况,提供了最新的概述和数据,以更好地了解猴痘病流行病学方面的知识和研究差距,并提供了控制当前多国爆发的有用措施。