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一例由勃勒纳瘤引起的假性梅格斯综合征病例。

A case of Pseudo-Meigs' syndrome due to Brenner tumor.

作者信息

Abe Tetsuya, Saida Tsukasa, Fujieda Kaoru, Inoue Kei, Satoh Toyomi, Nakajima Takahito

机构信息

Department of Radiology, University of Tsukuba Hospital, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan.

Department of Radiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.

出版信息

Radiol Case Rep. 2023 Jan 21;18(3):1349-1352. doi: 10.1016/j.radcr.2023.01.003. eCollection 2023 Mar.

DOI:10.1016/j.radcr.2023.01.003
PMID:36712189
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9873576/
Abstract

A 65-year-old woman with suspected ascites-associated abdominal distention had elevated CA125 levels. Contrast-enhanced computed tomography to search for the cause of the ascites showed bilateral pleural effusions, ascites, and an ovarian tumor. On magnetic resonance imaging the tumor exhibited a lobulated structure and markedly low signal intensity on both T1- and T2-weighted imaging, with no restrictions on diffusion-weighted images. Progressive enhancement was observed at tumor margins. Meigs syndrome due to fibroma was suspected, and total hysterectomy, bilateral salpingo-oophorectomy, and partial omentectomy were performed. Postoperatively, the pleural effusion and ascites resolved promptly without specific treatment. On pathological examination, the ovarian tumor was diagnosed as a benign Brenner tumor with scattered nests of transitional epithelium within a large amount of stroma. Based on the clinical course, the patient was diagnosed with pseudo-Meigs' syndrome due to a Brenner tumor.

摘要

一名65岁疑似腹水相关腹胀的女性,其CA125水平升高。为寻找腹水病因进行的对比增强计算机断层扫描显示双侧胸腔积液、腹水及一个卵巢肿瘤。磁共振成像显示肿瘤呈分叶状结构,在T1加权成像和T2加权成像上均表现为明显低信号强度,弥散加权成像无受限。在肿瘤边缘观察到渐进性强化。怀疑为纤维瘤所致的梅格斯综合征,遂行全子宫切除术、双侧输卵管卵巢切除术及部分大网膜切除术。术后,未经特殊治疗,胸腔积液和腹水迅速消退。病理检查显示,卵巢肿瘤被诊断为良性布伦纳瘤,在大量间质内可见散在的移行上皮巢。根据临床病程,该患者被诊断为布伦纳瘤所致的假性梅格斯综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daa4/9873576/2067ef0a3d91/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daa4/9873576/f58e2f1fd85c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daa4/9873576/512e0383961e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daa4/9873576/2067ef0a3d91/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daa4/9873576/f58e2f1fd85c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daa4/9873576/512e0383961e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daa4/9873576/2067ef0a3d91/gr3.jpg

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引用本文的文献

1
A Case Report of Meigs' Syndrome Caused by Ovarian Fibrothecoma with High Levels of CA125.一例由伴有高水平CA125的卵巢纤维卵泡膜瘤引起的梅格斯综合征病例报告
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本文引用的文献

1
Benign Brenner tumour of the ovary: CT and MRI features.卵巢良性 Brenner 肿瘤:CT 和 MRI 特征。
Clin Radiol. 2021 Aug;76(8):593-598. doi: 10.1016/j.crad.2021.03.018. Epub 2021 Apr 28.
2
Coexistence of benign struma ovarii, pseudo-Meigs' syndrome and elevated serum CA 125: Case report and review of the literature.卵巢良性甲状腺肿、假性梅格斯综合征与血清CA 125升高并存:病例报告及文献复习
Oncol Lett. 2015 Apr;9(4):1739-1742. doi: 10.3892/ol.2015.2927. Epub 2015 Feb 3.
3
Meigs' syndrome with an elevated CA 125 from benign Brenner tumors.
梅格斯综合征合并良性布伦纳瘤导致的CA 125升高。
Obstet Gynecol. 2001 Nov;98(5 Pt 2):980-2. doi: 10.1016/s0029-7844(01)01562-9.
4
Brenner tumor of the ovary: CT and MR findings.卵巢 Brenner 瘤:CT 与 MR 表现
J Comput Assist Tomogr. 2000 Jan-Feb;24(1):72-6. doi: 10.1097/00004728-200001000-00015.