普萘洛尔所致精神病：仍未被认识到？
Psychosis with propranolol: still not recognized?
作者信息
Cunnane J G, Blackwood G W
机构信息
Department of Psychiatry, St. James' University Hospital, Leeds, UK.
出版信息
Postgrad Med J. 1987 Jan;63(735):57-8. doi: 10.1136/pgmj.63.735.57.
Abstract
A 21 year old male developed hallucinations, personality change and severe depression following an increase in oral propranolol administration at recommended dosage levels. The symptoms improved markedly on stopping the drug. Without provocation, the patient developed further symptoms, mainly depressive, with marked suicidal impulses. Again, this quickly settled. The case identifies the need for careful observation of patients with psychiatric side effects from propranolol, following discontinuation of the drug.
摘要
一名21岁男性在按推荐剂量增加口服普萘洛尔后出现幻觉、人格改变和严重抑郁。停药后症状明显改善。在没有诱因的情况下，患者再次出现症状，主要是抑郁，并伴有明显的自杀冲动。症状再次迅速缓解。该病例表明，在停用普萘洛尔后，有必要对出现精神科副作用的患者进行仔细观察。
相似文献
1
Psychosis with propranolol: still not recognized?普萘洛尔所致精神病：仍未被认识到？
Postgrad Med J. 1987 Jan;63(735):57-8. doi: 10.1136/pgmj.63.735.57.
2
Propranolol-induced psychosis.普萘洛尔诱发的精神病。
Drug Intell Clin Pharm. 1984 Jul-Aug;18(7-8):601-3. doi: 10.1177/106002808401800709.
3
Propranolol-induced depression and psychosis.普萘洛尔诱发的抑郁和精神病。
Clin Pharm. 1985 Mar-Apr;4(2):214-8.
4
Propranolol psychosis.普萘洛尔所致精神病
Med J Aust. 1980 Feb 23;1(4):184-5. doi: 10.5694/j.1326-5377.1980.tb134746.x.
5
Propranolol psychosis.普萘洛尔所致精神病
Br J Psychiatry. 1976 Nov;129:508-9. doi: 10.1192/bjp.129.5.508b.
6
Propranolol withdrawal in psychosis.精神病患者停用普萘洛尔
Am J Psychiatry. 1990 Apr;147(4):534-5. doi: 10.1176/ajp.147.4.534b.
7
Psychosis with oral doses of propranolol.口服普萘洛尔导致的精神病
Ann Intern Med. 1979 Sep;91(3):496. doi: 10.7326/0003-4819-91-3-496_1.
8
[Schizophrenia-like psychosis following administration of propranol].服用普萘洛尔后出现的精神分裂症样精神病
MMW Munch Med Wochenschr. 1977 Apr 1;119(13):443-4.
9
Psychosis with ordinary doses of propranolol.普通剂量普萘洛尔所致精神病
Ann Intern Med. 1979 Jun;90(6):938-9. doi: 10.7326/0003-4819-90-6-938.
10
Propranolol-associated confused states during alcohol withdrawal.酒精戒断期间普萘洛尔相关的意识模糊状态。
J Clin Psychopharmacol. 1983 Jun;3(3):185-7.
引用本文的文献
1
β-Blockers and risk of neuropsychiatric disorders: A systematic review and meta-analysis.β受体阻滞剂与神经精神疾病风险：一项系统评价与荟萃分析
Br J Clin Pharmacol. 2025 Feb;91(2):325-337. doi: 10.1111/bcp.16361. Epub 2024 Dec 10.
2
Delayed-Onset Hypnopompic Visual Hallucinations 20 Years After Initiation of Propranolol Therapy for Systemic Hypertension: A Case Report.普萘洛尔治疗系统性高血压 20 年后迟发性催眠幻觉发作：病例报告。
Am J Case Rep. 2024 Jul 25;25:e944342. doi: 10.12659/AJCR.944342.
3
When No Treatment Is the Treatment: Mental Illness-Related Case Report.当无为即治疗：与精神疾病相关的病例报告
Can J Hosp Pharm. 2022 Winter;75(1):58-61. doi: 10.4212/cjhp.v75i1.3063.
4
The Importance of Medicinal Chemistry Knowledge in the Clinical Pharmacist's Education.医学化学知识在临床药师教育中的重要性。
Am J Pharm Educ. 2018 Mar;82(2):6083. doi: 10.5688/ajpe6083.
5
Psychiatric side effects of medications prescribed in internal medicine.内科开具药物的精神科副作用。
Dialogues Clin Neurosci. 2003 Jun;5(2):155-65. doi: 10.31887/DCNS.2003.5.2/rcasagrandetango.
6
Therapeutic uses of beta-adrenoceptor blocking drugs in the central nervous system in man.β-肾上腺素能受体阻断药物在人体中枢神经系统中的治疗用途。
Postgrad Med J. 1989 Jan;65(759):1-6. doi: 10.1136/pgmj.65.759.1.
本文引用的文献
1
Propranolol and white rabbits.普萘洛尔与白兔。
N Engl J Med. 1982 Aug 26;307(9):558-9.
2
Propranolol and depression.普萘洛尔与抑郁症
Am J Psychiatry. 1982 Jan;139(1):92-4. doi: 10.1176/ajp.139.1.92.
3
Psychiatric side effects of antihypertensive drugs other than reserpine.除利血平之外的抗高血压药物的精神科副作用。
J Clin Psychopharmacol. 1982 Feb;2(1):14-39. doi: 10.1097/00004714-198202000-00004.
4
Unwanted effects of propranolol.普萘洛尔的不良反应。
Am J Cardiol. 1966 Sep;18(3):463-72. doi: 10.1016/0002-9149(66)90071-3.
5
Propranolol and depression revisited: three cases and a review.再谈普萘洛尔与抑郁症：三例病例及文献综述
J Nerv Ment Dis. 1985 Feb;173(2):118-9. doi: 10.1097/00005053-198502000-00010.
6
Visual hallucinations and illusions with propranolol.
Br Med J. 1978 May 6;1(6121):1182. doi: 10.1136/bmj.1.6121.1182.
7
Psychosis with ordinary doses of propranolol.普通剂量普萘洛尔所致精神病
Ann Intern Med. 1979 Jun;90(6):938-9. doi: 10.7326/0003-4819-90-6-938.
Zotero 插件