Petrie W M, Maffucci R J, Woosley R L
Am J Psychiatry. 1982 Jan;139(1):92-4. doi: 10.1176/ajp.139.1.92.
The authors report the cases of 3 patients who had depressive episodes after administration of propranolol for medical illnesses. The depressive episodes were severe, occurred in a dose-dependent manner, and promptly remitted when propranolol was discontinued. Physicians' awareness of this complication, especially in cases of patients with a history of depression, may reduce the occurrence of this drug reaction.
作者报告了3例因治疗疾病服用普萘洛尔后出现抑郁发作的病例。抑郁发作严重，呈剂量依赖性，停用普萘洛尔后迅速缓解。医生了解这种并发症，尤其是有抑郁症病史的患者，可能会减少这种药物反应的发生。
