Pan Wenjun, Zhang Zhuqi, Zhang Yuzhuo, Lu Haining, Wang Baohua, Zhao Shaoyang, Li Saimei
Postdoctoral Research Station, Guangzhou University of Chinese Medicine, Guangzhou, China.
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Front Nutr. 2023 Jan 11;9:981302. doi: 10.3389/fnut.2022.981302. eCollection 2022.
Retinopathy is a chronic inflammatory disease whose prognosis could be improved with dietary interventions. However, the association between a pro-inflammatory diet and the prevalence of retinopathy has not been fully elucidated. We assess the association between the dietary inflammatory index (DII), which is a comprehensive index determining inflammatory potential derived from food parameters according to literature, and the prevalence of retinopathy based on the data from the National Health and Nutritional Examination Survey (NHANES) 2005-2008 involving 2,403 participants. Energy-adjusted DII (E-DII) was not related to the occurrence of retinopathy in the general, non-diabetic, or middle-aged participants. In the diabetic and aged participants, one unit increment of E-DII accounted for 14 and 15% higher the prevalence of retinopathy respectively. The highest E-DII group had a 78 and 79% higher prevalence of retinopathy than the lowest group respectively. After adjusting for several covariables, the highest E-DII group was still associated with a 68% increase in retinopathy in diabetic patients. These results suggest that E-DII is positively associated with the prevalence of diabetic retinopathy among diabetic patients.
视网膜病变是一种慢性炎症性疾病，饮食干预可改善其预后。然而，促炎性饮食与视网膜病变患病率之间的关联尚未完全阐明。我们根据2005 - 2008年美国国家健康与营养检查调查（NHANES）中2403名参与者的数据，评估饮食炎症指数（DII）（这是一个根据文献从食物参数确定炎症潜力的综合指数）与视网膜病变患病率之间的关联。能量调整后的DII（E - DII）与一般人群、非糖尿病患者或中年参与者的视网膜病变发生无关。在糖尿病患者和老年参与者中，E - DII每增加一个单位，视网膜病变患病率分别高出14%和15%。E - DII最高组的视网膜病变患病率分别比最低组高出78%和79%。在调整了几个协变量后，E - DII最高组仍与糖尿病患者视网膜病变增加68%相关。这些结果表明，E - DII与糖尿病患者中糖尿病视网膜病变的患病率呈正相关。
