乙酰唑胺对高原屏气的影响。
The effect of acetazolamide on breath holding at high altitude.
作者信息
Morrissey S C, Keohane K, Coote J H
机构信息
Department of Physiology, Medical School, University of Birmingham, Edgbaston, UK.
出版信息
Postgrad Med J. 1987 Mar;63(737):189-90. doi: 10.1136/pgmj.63.737.189.
The effect of altitude and acetazolamide on breath holding was studied in 20 individuals. Breath holding time was reduced progressively during ascent. There was an additional reduction in the acetazolamide group at low but not at high altitude. The initial difference between the two groups may have been related to a lower CSF pH when on acetazolamide. At high altitude the finding of similar breath holding times in the two groups may have been due to acclimatization in the placebo group.
在20名个体中研究了海拔高度和乙酰唑胺对屏气的影响。在上升过程中屏气时间逐渐减少。在低海拔时，乙酰唑胺组有额外的减少，但在高海拔时没有。两组之间最初的差异可能与服用乙酰唑胺时脑脊液pH值较低有关。在高海拔时，两组屏气时间相似的结果可能是由于安慰剂组的适应作用。
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