Ngankam Deklerk A, Crozier Kelley, Vu Anh-Thu
Physical Medicine and Rehabilitation, University of Pittsburgh Medical Center, Pittsburgh, USA.
Physical Medicine and Rehabilitation, Reading Hospital Rehabilitation at Wyomissing, Reading, USA.
Cureus. 2022 Dec 25;14(12):e32927. doi: 10.7759/cureus.32927. eCollection 2022 Dec.
We reviewed the published literature on rehabilitation outcomes in patients with cortical blindness (CB) and highlighted the characteristic features and prognosis of CB due to cardiac arrest. The studies excluded were those involving the pediatric population (<age 16), written in a language other than English, and studies with no mention of outcomes. The literature search was done by PubMed and EBSCOhost databases from the oldest available literature through November 2019. Due to the scarcity of published literature and a qualitative description of outcomes, a narrative review of the literature was deemed appropriate. Seven case reports and one retrospective cohort study met the inclusion criteria. Cognitive and visual impairments were significant barriers to rehabilitation in CB. Improvement of visual deficits occurred within one to two months. Those with complete blindness, cognitive impairments, and a delay in resuscitation were more likely to have poorer functional outcomes in the performance of activities of daily living and were less likely to be discharged home. This is the most comprehensive review of published literature to focus on the function of patients with cortical blindness. The limitations include the small number of published literature and the qualitative approach utilized. Despite the limitations, the findings of this review can inform future studies that would investigate the most efficient and comprehensive methods of CB rehabilitation.
我们回顾了已发表的关于皮质盲（CB）患者康复结局的文献，并强调了心脏骤停所致CB的特征和预后。排除的研究包括涉及儿科人群（年龄<16岁）、非英文撰写的研究以及未提及结局的研究。文献检索通过PubMed和EBSCOhost数据库进行，检索范围从可获取的最早期文献至2019年11月。由于已发表文献稀缺且对结局为定性描述，因此认为对文献进行叙述性综述是合适的。七篇病例报告和一项回顾性队列研究符合纳入标准。认知和视力障碍是CB康复的重大障碍。视力缺陷在一至两个月内有所改善。完全失明、有认知障碍以及复苏延迟的患者在日常生活活动表现中功能结局更可能较差，且出院回家的可能性较小。这是已发表文献中最全面的聚焦于皮质盲患者功能的综述。局限性包括已发表文献数量少以及采用的定性方法。尽管存在局限性，但本综述的结果可为未来研究提供参考，这些研究将探究皮质盲康复最有效和全面的方法。
