Jain Hanish, Murali Sindhubarathi, Singh Garima, Amzuta Ioana
Internal Medicine, Upstate University Hospital, Syracuse, USA.
Medicine, State University of New York Upstate Medical University Hospital, Syracuse, USA.
Cureus. 2022 Dec 25;14(12):e32913. doi: 10.7759/cureus.32913. eCollection 2022 Dec.
Hypercalcemic crisis due to severe decompensated hypercalcemia represents a life-threatening medical emergency leading to renal failure and altered mental status. Hypercalcemic crisis most commonly results from hypercalcemia of malignancy, undiagnosed primary hyperparathyroidism, granulomatous diseases, and medication-induced hypercalcemia. Commonly prescribed medications like thiazide diuretics, lithium therapy, and teriparatide are among the medications known to cause hypercalcemia. Here, we describe a case of the hypercalcemic crisis caused by excessive calcium carbonate ingestion emphasizing physicians to be aware of this potentially life-threatening adverse effect of a widely available over-the-counter acid reflux medication and educate patients regarding the same.
严重失代偿性高钙血症所致的高钙血症危象是一种危及生命的医疗急症,可导致肾衰竭和精神状态改变。高钙血症危象最常见的病因是恶性肿瘤引起的高钙血症、未诊断的原发性甲状旁腺功能亢进、肉芽肿性疾病以及药物性高钙血症。噻嗪类利尿剂、锂盐治疗药物和特立帕肽等常用药物是已知可引起高钙血症的药物。在此,我们描述一例因过量摄入碳酸钙导致高钙血症危象的病例,强调医生应意识到这种广泛使用的非处方抗酸反流药物可能存在的危及生命的不良反应,并就相关问题对患者进行教育。