病例报告：两性霉素 B 和甲氟喹作为肺包虫病的挽救治疗方法。
Case Report: Amphotericin B and Mefloquine as a Salvage Treatment of Alveolar Echinococcosis.
机构信息
University Hospital for Infectious Diseases Zagreb, Zagreb, Croatia.
School of Medicine, University of Zagreb, Zagreb, Croatia.
出版信息
Am J Trop Med Hyg. 2023 Jan 30;108(3):581-583. doi: 10.4269/ajtmh.22-0465. Print 2023 Mar 1.
Abstract
Alveolar echinococcosis is an emerging zoonotic disease caused by the parasite Echinococcus multilocularis. Most patients are diagnosed at a late stage, when lifelong treatment with benzimidazoles is required to stop disease progression. However, for patients who do not tolerate benzimidazole therapy, there are no alternatives. Here, we present a patient with advanced alveolar echinococcosis who was successfully treated with amphotericin B deoxycholate and mefloquine as a rescue therapy after he developed albendazole intolerance.
摘要
泡型包虫病是一种由多房棘球绦虫引起的新发人畜共患寄生虫病。大多数患者在晚期被诊断出来，此时需要终身使用苯并咪唑类药物治疗以阻止疾病进展。然而，对于不能耐受苯并咪唑类药物治疗的患者，尚无其他替代药物。在这里，我们报告了 1 例晚期泡型包虫病患者，在他对阿苯达唑不耐受后，用两性霉素 B 去氧胆酸盐和甲氟喹进行了挽救治疗，取得了成功。
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