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Longitudinal Effects of 1-Year Smoking Cessation on Human Bronchial Epithelial Transcriptome.

作者信息

Rathnayake Senani N H, Ditz Benedikt, Willemse Brigitte W M, Timens Wim, Kooistra Wierd, Heijink Irene H, Oliver Brian G G, van den Berge Maarten, Faiz Alen

机构信息

Respiratory Bioinformatics and Molecular Biology Group, The University of Technology Sydney, Sydney, NSW, Australia; School of Life Sciences, The University of Technology Sydney, Ultimo, NSW, Australia; Respiratory Cellular and Molecular Biology Group, Woolcock Institute of Medical Research, Sydney, NSW, Australia.

Groningen Research Institute for Asthma and COPD, University of Groningen, Groningen, The Netherlands; Department of Pulmonary Diseases,University Medical Centre Groningen, Groningen, The Netherlands.

出版信息

Chest. 2023 Jul;164(1):85-89. doi: 10.1016/j.chest.2022.12.050. Epub 2023 Jan 28.

DOI:10.1016/j.chest.2022.12.050
PMID:
36716955
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10331623/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3b0/10331623/4a31e1dfa6de/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3b0/10331623/4a31e1dfa6de/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3b0/10331623/4a31e1dfa6de/gr1.jpg

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Compartmentalization of anti-oxidant and anti-inflammatory gene expression in current and former smokers with COPD.在 COPD 患者中,目前吸烟者和曾吸烟者的抗氧化和抗炎基因表达的分隔化。
Respir Res. 2019 Aug 20;20(1):190. doi: 10.1186/s12931-019-1164-1.
3
A cellular census of human lungs identifies novel cell states in health and in asthma.
对人类肺部的细胞普查鉴定了健康和哮喘中的新型细胞状态。
Nat Med. 2019 Jul;25(7):1153-1163. doi: 10.1038/s41591-019-0468-5. Epub 2019 Jun 17.
4
Tobacco-Related Alterations in Airway Gene Expression are Rapidly Reversed Within Weeks Following Smoking-Cessation.戒烟数周内,气道基因表达的烟草相关改变迅速逆转。
Sci Rep. 2019 May 6;9(1):6978. doi: 10.1038/s41598-019-43295-3.
5
Serum periostin does not reflect type 2-driven inflammation in COPD.血清骨膜蛋白不能反映 COPD 中的 2 型驱动炎症。
Respir Res. 2018 Jun 7;19(1):112. doi: 10.1186/s12931-018-0818-8.
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J Allergy Clin Immunol. 2018 Jul;142(1):314-317.e15. doi: 10.1016/j.jaci.2018.01.047. Epub 2018 Mar 6.
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