Sirivella Martin L, Rahinj Ganesh B, Chauhan Harshit S, Satyanarayana Menta V, Ramanan Laxminarayanan
Research and Development Department, Sahajanand Medical Technologies (SMT) Ltd., Surat, India.
Cardiovasc Eng Technol. 2023 Apr;14(2):315-330. doi: 10.1007/s13239-022-00653-z. Epub 2023 Jan 30.
During percutaneous coronary intervention (PCI), the ability to navigate a catheter without causing injury to the vessel and damage to the device is crucial outcome of the procedure. This study aimed to develop a numerical model to analyse the percutaneous transluminal coronary angioplasty (PTCA) catheter navigation in coronary vessels.
Trackability and pushability are two major parameters used to characterize the navigation of PTCA balloon catheters, and they are influenced by vessel tortuosity, contact interactions and catheter design. In the current study, finite element analysis model is presented to evaluate trackability and pushability considering two different vessel geometries. Impact of contact interactions among catheter, guidewire, and vessel were studied to validate the numerical model with in vitro test data. Further, a parametric study was conducted to understand the influence of distal shaft, and proximal shaft outer diameter.
Obtained results suggest that contact interaction and co-efficient of friction between guidewire and catheter are critical parameters to obtain numerical results comparable to experimental data. Results from the parametric study predicted strong positive correlation of distal shaft diameter on pushability, and weak correlation on trackability force. Furthermore, parametric variation in proximal shaft diameter has strong positive correlation on trackability force and strong negative correlation on pushability.
Numerical methodology presented in this study is a preliminary attempt to simulate the behavior of PTCA balloon catheter navigation. This methodology will be helpful in the design and optimization of PTCA balloon catheter and similar devices with improved deliverability.
在经皮冠状动脉介入治疗（PCI）过程中，使导管在不损伤血管和不损坏设备的情况下顺利通过是该手术的关键结果。本研究旨在建立一个数值模型，以分析经皮腔内冠状动脉成形术（PTCA）导管在冠状动脉中的导航情况。
可跟踪性和可推送性是用于表征PTCA球囊导管导航的两个主要参数，它们受血管弯曲度、接触相互作用和导管设计的影响。在本研究中，提出了有限元分析模型，以评估考虑两种不同血管几何形状时的可跟踪性和可推送性。研究了导管、导丝和血管之间接触相互作用的影响，并用体外测试数据验证了数值模型。此外，还进行了参数研究，以了解远端杆和近端杆外径的影响。
获得的结果表明，导丝与导管之间的接触相互作用和摩擦系数是获得与实验数据可比的数值结果的关键参数。参数研究的结果预测，远端杆直径与可推送性呈强正相关，与可跟踪力呈弱相关。此外，近端杆直径的参数变化与可跟踪力呈强正相关，与可推送性呈强负相关。
本研究中提出的数值方法是模拟PTCA球囊导管导航行为的初步尝试。该方法将有助于PTCA球囊导管及类似输送性能更佳的设备的设计和优化。
