Department of Chemistry, College of Science, Shanghai University, Shanghai, 200444, China.
Key Lab of Nanodevices and Applications, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, China.
Angew Chem Int Ed Engl. 2023 Mar 13;62(12):e202218055. doi: 10.1002/anie.202218055. Epub 2023 Feb 14.
Non-metallic materials have emerged as a new family of active substrates for surface-enhanced Raman scattering (SERS), with unique advantages over their metal counterparts. However, owing to their inefficient interaction with the incident wavelength, the Raman enhancement achieved with non-metallic materials is considerably lower with respect to the metallic ones. Herein, we propose colourful semiconductor-based SERS substrates for the first time by utilizing a Fabry-Pérot cavity, which realize a large freedom in manipulating light. Owing to the delicate adjustment of the absorption in terms of both frequency and intensity, resonant absorption can be achieved with a variety of non-metal SERS substrates, with the sensitivity further enhanced by ≈100 times. As a typical example, by introducing a Fabry-Pérot-type substrate fabricated with SiO /Si, a rather low detection limit of 10 M for the SARS-CoV-2S protein is achieved on SnS . This study provides a realistic strategy for increasing SERS sensitivity when semiconductors are employed as SERS substrates.
非金属材料作为表面增强拉曼散射（SERS）的新型活性衬底已经出现，与金属材料相比具有独特的优势。然而，由于它们与入射波长的相互作用效率较低，因此与金属材料相比，非金属材料的拉曼增强要低得多。在这里，我们首次通过利用法布里-珀罗腔提出了基于彩色半导体的 SERS 衬底，从而在操控光方面实现了较大的自由度。由于频率和强度方面的吸收都可以进行精细调节，可以实现多种非金属 SERS 衬底的共振吸收，从而将灵敏度提高约 100 倍。作为一个典型的例子，通过引入由 SiO2/Si 制成的法布里-珀罗型衬底，在 SnS2 上实现了对 SARS-CoV-2 S 蛋白的低至 10-10 M 的检测限。该研究为在将半导体用作 SERS 衬底时提高 SERS 灵敏度提供了一种现实策略。
