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非洲抗生素滥用和自我药疗的教育干预措施:系统评价与荟萃分析[方案]

Educational Interventions for Antibiotics Misuse and Self-Medication in Africa: A Systematic Review and Meta-Analysis [Protocol].

作者信息

Misau Y A, Mogere D, Mbaruk S, Usman U S, Bello S, Oduwole O, Moriam C

机构信息

Department of Community Medicine College of Medical Sciences, Abubakar Tafawa Balewa University, Bauchi State, Nigeria.

Department of Epidemiology and Biostatistics, School of Public Health, Mount Kenya University, Thika Kenya.

出版信息

West Afr J Med. 2023 Jan 30;40(1):114-120.

PMID:36718718
Abstract

BACKGROUND

Antibiotics misuse and self-medication remains one of the most serious public health challenges globally. Persistent rise in resistant bacterial infections has been attributed to high prevalence of antibiotics misuse and self-medication. Large volume of literature has emerged describing studies that evaluate the effectiveness of various types and combinations of educational and behavior-modification techniques to reduce antibiotics misuse and self-medication. No previous systemic review has attempted to assess the quality of evidence in public domains on educational strategies aiming to reduce prevalence and improve knowledge, attitude and practice on antibiotics misuse and self-medication in Africa. This study, therefore, intends to assess the quality of evidence presented and determine the effectiveness of health education as an intervention tool for reducing prevalence and improving knowledge and attitude on antibiotics misuse and self-medication among adults in Africa.

METHODS

This study will include published papers on effectiveness of health education in reducing antibiotics misuse and self-medication from 2011-2021. Systematic search for literature will be conducted according to the Preferred Reporting Item for Systematic Reviews and Meat-analysis (PRISMA) guidelines to identify published studies based on our predetermined inclusion and exclusion criteria in PubMed, EMBASE, PsychINFO, CINAHL and Web of Sciences. Two independent reviewers will assess all identified studies and another set of reviewers will extract data for analysis and evidence synthesis.

摘要

背景

抗生素的滥用和自我药疗仍然是全球最严重的公共卫生挑战之一。耐药细菌感染的持续增加归因于抗生素滥用和自我药疗的高流行率。大量文献描述了评估各种类型和组合的教育及行为修正技术以减少抗生素滥用和自我药疗有效性的研究。此前没有系统评价试图评估旨在降低非洲抗生素滥用和自我药疗的流行率并改善相关知识、态度和行为的公共领域教育策略的证据质量。因此,本研究旨在评估所呈现证据的质量,并确定健康教育作为一种干预工具在降低非洲成年人抗生素滥用和自我药疗的流行率以及改善相关知识和态度方面的有效性。

方法

本研究将纳入2011年至2021年期间发表的关于健康教育在减少抗生素滥用和自我药疗方面有效性的数据。将根据系统评价和荟萃分析的首选报告项目(PRISMA)指南进行文献的系统检索,以根据我们预先确定的纳入和排除标准在PubMed、EMBASE、PsychINFO、CINAHL和科学网中识别已发表的研究。两名独立的评审员将评估所有识别出的研究,另一组评审员将提取数据进行分析和证据综合。

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