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一种胎盘植入谱系疾病管理的新方法:越南图杜医院单中心多学科手术经验。

A novel approach in the management of placenta accreta spectrum disorders: A single-center multidisciplinary surgical experience at Tu Du Hospital in Vietnam.

机构信息

Department of High-risk Pregnancy, Tu Du Hospital, Ho Chi Minh City, Viet Nam.

Department of Obstetrics and Gynecology, Ho Chi Minh University of Medicine and Pharmacy, Viet Nam.

出版信息

Taiwan J Obstet Gynecol. 2023 Jan;62(1):22-30. doi: 10.1016/j.tjog.2022.09.003.

DOI:10.1016/j.tjog.2022.09.003
PMID:36720545
Abstract

OBJECTIVE

Placenta accreta spectrum disorders (PASD) are the leading cause which results in highly maternal mortality during pregnancy. Although hysterectomy has been the gold standard for PASD, the recent study along with our experience has been demonstrated that the association between uterine myometrial resection and transverse B-Lynch suture in conservative management might be effective in the appropriate patients, thus we hereby attempted to determine this issue.

MATERIALS AND METHODS

A retrospective observational study enrolled 65 patients at Tu Du Hospital in Vietnam between January 2017 and December 2018. This study included all pregnant women above 28 weeks of gestational age, who had undergone cesarean delivery due to PASD diagnosed preoperatively by ultrasound or upon laparotomy. Additionally, all patients who desired uterine preservation underwent modified one-step conservative uterine surgery (MOSCUS), avoiding peripartum hysterectomy.

RESULTS

Overall, the rate of successful preservation was 93.8%. Other main outcomes such as average operative blood loss was 987 mL, mean blood transfusion was 831 ± 672 mL; mean operative time was 135 ± 31 min and average postoperative time was 5.79 days. Postoperative complications included six out of 65 cases due to intraoperative bleeding and postoperative infection, requiring hysterectomy in 4 patients.

CONCLUSION

MOSCUS was associated with less operative blood loss and blood transfusion amount. Its success rate of uterine preservation was approximately 94% in our study. Thus, this method can be acceptable in PASD management at our maternity health care center. Further studies might be necessary to evaluate the long-term effects of this method in PASD management.

摘要

目的

胎盘植入谱系疾病(PASD)是导致妊娠期间产妇死亡率居高不下的主要原因。虽然子宫切除术一直是 PASD 的金标准,但最近的研究和我们的经验表明,在适当的患者中,保守治疗中子宫肌层切除术和横向 B-Lynch 缝合的联合可能是有效的,因此我们试图确定这个问题。

材料和方法

这是一项在越南图杜医院进行的回顾性观察研究,纳入了 2017 年 1 月至 2018 年 12 月期间的 65 名患者。本研究包括所有 28 周以上妊娠的孕妇,这些孕妇因术前超声或剖腹术诊断 PASD 而行剖宫产。此外,所有希望保留子宫的患者均接受改良一步式保守性子宫手术(MOSCUS),避免围产期子宫切除术。

结果

总的来说,成功保留子宫的比例为 93.8%。其他主要结果包括平均手术出血量为 987ml,平均输血 831±672ml;平均手术时间为 135±31 分钟,平均术后时间为 5.79 天。术后并发症包括 65 例中有 6 例因术中出血和术后感染需要行子宫切除术。

结论

MOSCUS 与术中出血量和输血量减少有关。在我们的研究中,保留子宫的成功率约为 94%。因此,这种方法在我们的产科保健中心 PASD 管理中是可以接受的。进一步的研究可能有必要评估这种方法在 PASD 管理中的长期效果。

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