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使用乙醇硬化疗法治疗大型颈部淋巴管瘤。

The Use of Ethanol Sclerotherapy To Treat a Large Cervical Lymphocele.

作者信息

Shaver Timothy B, El Shatanofy Muhammad, Niermeyer Weston, Joshi Arjun

机构信息

Otolaryngology - Head and Neck Surgery, George Washington University School of Medicine and Health Sciences, Washington, D.C., USA.

Division of Otolaryngology - Head and Neck Surgery, George Washington University School of Medicine and Health Sciences, Washington, D.C., USA.

出版信息

Cureus. 2022 Dec 28;14(12):e33043. doi: 10.7759/cureus.33043. eCollection 2022 Dec.

DOI:10.7759/cureus.33043
PMID:36721545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9881499/
Abstract

Cervical lymphoceles are atypical lymphatic accumulations that develop within the subcutaneous tissue of the neck. While these accumulations have traditionally been removed via surgical excision, sclerotherapy has recently emerged as a reasonable option to prevent injury to surrounding vascular, neurologic, and pulmonary structures. The purpose of this case report is to describe the efficacy of ethanol sclerotherapy for a cervical lymphocele refractory to surgical embolization. We present the case of a 70-year-old male with a large cervical lymphocele that was initially treated with surgical embolization. The mass rapidly reaccumulated within two weeks and the patient subsequently underwent ethanol sclerotherapy with no evidence of re-accumulation after 18 months. This case highlights the utility of ethanol due to its better side-effect profile, widespread availability, and cheaper cost when compared to better-described agents.

摘要

颈部淋巴管瘤是在颈部皮下组织内形成的非典型淋巴液积聚。虽然这些积聚传统上是通过手术切除来消除的,但硬化疗法最近已成为一种合理的选择,可防止对周围血管、神经和肺部结构造成损伤。本病例报告的目的是描述乙醇硬化疗法对手术栓塞难治性颈部淋巴管瘤的疗效。我们报告一例70岁男性患者,患有巨大颈部淋巴管瘤,最初接受了手术栓塞治疗。肿块在两周内迅速重新积聚,随后患者接受了乙醇硬化疗法,18个月后未见重新积聚迹象。与其他已详细描述的药物相比,本病例突出了乙醇的效用,因其副作用较小、易于获取且成本较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e09/9881499/9e98e64470ef/cureus-0014-00000033043-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e09/9881499/372d13cf63b7/cureus-0014-00000033043-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e09/9881499/7ec756ea165f/cureus-0014-00000033043-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e09/9881499/9e98e64470ef/cureus-0014-00000033043-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e09/9881499/372d13cf63b7/cureus-0014-00000033043-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e09/9881499/7ec756ea165f/cureus-0014-00000033043-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e09/9881499/9e98e64470ef/cureus-0014-00000033043-i03.jpg

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本文引用的文献

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Efficacy and Safety of Ethanol Ablation for Branchial Cleft Cysts.乙醇消融治疗鳃裂囊肿的疗效和安全性。
AJNR Am J Neuroradiol. 2017 Dec;38(12):2351-2356. doi: 10.3174/ajnr.A5373. Epub 2017 Sep 28.
2
Ultrasound-guided sclerotherapy for benign non-thyroid cystic mass in the neck.超声引导下硬化治疗颈部良性非甲状腺囊性肿块。
Ultrasonography. 2014 Apr;33(2):83-90. doi: 10.14366/usg.13026. Epub 2014 Feb 26.
3
Cervical lymphocoele: a simple solution for a complicated problem.颈部淋巴管瘤:解决复杂问题的简单方法。
Ann R Coll Surg Engl. 2012 Mar;94(2):e79-80. doi: 10.1308/003588412X13171221500826.
4
Characteristic imaging findings in lymphoceles of the head and neck.头颈部淋巴管瘤的特征性影像学表现。
AJR Am J Roentgenol. 2011 Dec;197(6):1431-5. doi: 10.2214/AJR.10.6278.
5
Ethanol threshold doses for systemic complications during sclerotherapy of superficial venous malformations: a retrospective study.乙醇阈值剂量在表浅静脉畸形硬化治疗中引发系统性并发症的回顾性研究。
Neuroradiology. 2011 Nov;53(11):891-4. doi: 10.1007/s00234-010-0803-5. Epub 2010 Nov 27.
6
OK-432 sclerotherapy of cervical chylous lymphocele after neck dissection.颈部清扫术后颈乳糜性淋巴囊肿的OK-432硬化治疗
Laryngoscope. 2008 Jun;118(6):999-1002. doi: 10.1097/MLG.0b013e31816b657b.
7
Percutaneous transcatheter ethanol sclerotherapy and catheter drainage of postoperative pelvic lymphoceles.经皮经导管乙醇硬化疗法及术后盆腔淋巴囊肿的导管引流术
Cardiovasc Intervent Radiol. 2007 Mar-Apr;30(2):237-40. doi: 10.1007/s00270-006-0180-y.
8
Spontaneous cervical lymphocele.自发性颈淋巴管瘤
Head Neck. 2007 Jan;29(1):77-80. doi: 10.1002/hed.20484.
9
Percutaneous ethanol sclerotherapy of postoperative lymphoceles.术后淋巴囊肿的经皮乙醇硬化疗法
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