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甲黑线:病因、诊断与治疗

Melanonychia: Etiology, Diagnosis, and Treatment.

作者信息

Singal Archana, Bisherwal Kavita

机构信息

Department of Dermatology and STD, University College of Medical Sciences and GTB Hospital, New Delhi, India.

Department of Dermatology and STD, Lady Hardinge Medical College and SSK Hospital, New Delhi, India.

出版信息

Indian Dermatol Online J. 2020 Jan 13;11(1):1-11. doi: 10.4103/idoj.IDOJ_167_19. eCollection 2020 Jan-Feb.

Abstract

Melanonychia is a very worrisome entity for most patients. It is characterized by brownish black discoloration of nail plate and is a common cause of nail plate pigmentation. The aetiology of melanonychia ranges from more common benign causes to less common invasive and in situ melanomas. Melanonychia especially in a longitudinal band form can be due to both local and systemic causes. An understanding of the epidemiology, pathophysiology and clinical details is necessary for adequate patient care and counseling. It not only helps in the early recognition of melanoma but also prevents unnecessary invasive work up in cases with benign etiology. An early diagnosis of malignant lesion is the key to favourable outcome. Though there are no established guidelines or algorithms for evaluating melanonychia, a systematic stepwise approach has been suggested to arrive at a probable etiology. We, hereby, review the aetiology, clinical features, diagnostic modalities and management protocol for melanonychia.

摘要

对大多数患者来说,甲下黑素沉着是一个非常令人担忧的问题。它的特征是甲板出现棕黑色变色,是甲板色素沉着的常见原因。甲下黑素沉着的病因范围从较常见的良性原因到较不常见的侵袭性和原位黑色素瘤。尤其是纵向条纹状的甲下黑素沉着,可能由局部和全身原因引起。了解其流行病学、病理生理学和临床细节对于提供充分的患者护理和咨询是必要的。这不仅有助于早期识别黑色素瘤,还能避免对良性病因的病例进行不必要的侵入性检查。恶性病变的早期诊断是取得良好结果的关键。虽然目前尚无评估甲下黑素沉着的既定指南或算法,但已有人建议采用系统的逐步方法来确定可能的病因。在此,我们回顾甲下黑素沉着的病因、临床特征、诊断方法和管理方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0abc/7001389/2fa76ed03829/IDOJ-11-1-g001.jpg

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