在带绦虫 Schistocephalus solidus 的个体发生过程中外泌体的分泌。
Secretion of extracellular vesicles during ontogeny of the tapeworm Schistocephalus solidus.
机构信息
Institute of Parasitology, Biology Centre, Czech Academy of Sciences, Ceske Budejovice, Czech Republic.
Faculty of Science, University of South Bohemia, Ceske Budejovice, Czech Republic.
出版信息
Folia Parasitol (Praha). 2023 Jan 16;70:2023.003. doi: 10.14411/fp.2023.003.
We provide the first ultrastructural evidence of the secretion of extracellular vesicles (EVs) across all parasitic stages of the tapeworm Schistocephalus solidus (Müller, 1776) (Cestoda: Diphyllobothriidea) using a laboratory life cycle model. We confirmed the presence of EV-like bodies in all stages examined, including the hexacanth, procercoids in the copepod, Macrocyclops albidus (Jurine, 1820), plerocercoids from the body cavity of the three-spined stickleback, Gasterosteus aculeatus Linnaeus, and adults cultivated in artificial medium. In addition, we provide description of novel tegumental structures potentially involved in EV biogenesis and the presence of unique elongated EVs similar to those previously described only in Fasciola hepatica Linnaeus, 1758 (Trematoda), Hymenolepis diminuta (Rudolphi, 1819) (Cestoda), and Trypanosoma brucei Plimmer et Bradford, 1899 (Kinetoplastida).
我们使用实验室生活史模型，为带绦虫 Schistocephalus solidus（Müller，1776）（Cestoda：Diphyllobothriidea）的所有寄生阶段提供了细胞外囊泡（EV）分泌的首个超微结构证据。我们在所有检查阶段都证实了存在类似 EV 的体，包括六钩蚴、桡足类 Macrocyclops albidus（Jurine，1820）中的原尾蚴、三刺鱼体腔中的似囊尾蚴和在人工培养基中培养的成虫。此外，我们还描述了可能参与 EV 生物发生的新表皮结构以及存在独特的伸长 EV，这些 EV 类似于先前仅在 Fasciola hepatica Linnaeus，1758（吸虫纲）、Hymenolepis diminuta（Rudolphi，1819）（绦虫纲）和 Trypanosoma brucei Plimmer et Bradford，1899（动基体目）中描述的 EV。
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