Tahhan Nina, Naduvilath Thomas, Tilia Daniel
Brien Holden Vision Institute, Sydney, New South Wales, Australia.
School of Optometry and Vision Science, University of New South Wales, Sydney, New South Wales, Australia.
Ophthalmic Physiol Opt. 2023 May;43(3):418-425. doi: 10.1111/opo.13102. Epub 2023 Feb 1.
Myopia control (MC) studies in children link efficacy with subjective performance. There is little MC research in teenagers and young adults. This study compared subjective experience of MC contact lenses in different age groups.
Data were retrospectively reviewed from two double-masked, bilateral wear, crossover contact lens clinical trials (myopia -0.75D to -3.50D and <1.00 DC; 9-35 years). Participants wore two novel lenses (MC lenses with relative peripheral plus [+1.50D and +2.50D]) and a single-vision (SV) control lens (Clariti® 1 day) for 1 week each. All lenses were made from Somofilcon A material. Data collected included visual acuity (VA), wearing time, subjective ratings of comfort, distance and near vision clarity and overall vision. Generalised estimating equations with subject random intercepts and identity link functions were used in the analysis.
A total of 31 participants (10 children, 11 teenagers and 10 adults) were included, with no difference between the age groups for VA with the dispensed lenses (p > 0.05). All groups could discriminate between the SV and MC lenses for vision (distance, near and overall) after 1 week (p < 0.05). There was no difference between groups for comfort or distance and near vision. Children rated the overall vision quality higher than teenagers and adults for both SV and MC lenses (p < 0.05), but there was no difference relative to the SV lens between groups (p > 0.50). Daily wear time was lowest for children for all lens types (all p < 0.02). Wear time was positively associated with ratings of overall vision quality for children and young adults (both p < 0.05).
All age groups rated SV lenses higher than MC lenses. Subjective ratings of MC lenses appear similar between age groups relative to SV lenses. Wear time was lowest in children and was correlated with overall vision quality ratings in children and young adults.
儿童近视控制（MC）研究将疗效与主观表现联系起来。青少年和年轻人的MC研究较少。本研究比较了不同年龄组MC隐形眼镜的主观体验。
回顾性分析两项双盲、双侧佩戴、交叉隐形眼镜临床试验（近视-0.75D至-3.50D且散光<1.00DC；9至35岁）的数据。参与者分别佩戴两种新型镜片（相对周边加光[+1.50D和+2.50D]的MC镜片）和一种单焦点（SV）对照镜片（Clariti®1天型），每种镜片佩戴1周。所有镜片均由Somofilcon A材料制成。收集的数据包括视力（VA）、佩戴时间、舒适度主观评分、远视力和近视力清晰度以及总体视力。分析中使用了具有受试者随机截距和恒等连接函数的广义估计方程。
共纳入31名参与者（10名儿童、11名青少年和10名成年人），各年龄组佩戴所分发镜片后的视力无差异（p>0.05）。1周后，所有组都能区分SV和MC镜片的视力（远视力、近视力和总体视力）（p<0.05）。各组在舒适度、远视力和近视力方面无差异。对于SV和MC镜片，儿童对总体视力质量的评分均高于青少年和成年人（p<0.05），但各组相对于SV镜片无差异（p>0.50）。所有镜片类型中，儿童的每日佩戴时间最短（所有p<0.02）。儿童和年轻人的佩戴时间与总体视力质量评分呈正相关（均p<0.05）。
所有年龄组对SV镜片的评分均高于MC镜片。相对于SV镜片，各年龄组对MC镜片的主观评分似乎相似。儿童的佩戴时间最短，且与儿童和年轻人的总体视力质量评分相关。
