Sjölander Arvid
From the Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Epidemiology. 2023 Mar 1;34(2):186-191. doi: 10.1097/EDE.0000000000001567. Epub 2022 Dec 12.
In a seminal paper, Hernán et al. 2004 provided a systematic classification of selection biases, for scenarios where the selection is a collider between the exposure and the outcome. Hernán 2017 discussed another scenario, where the selection is statistically independent of the exposure, but associated with the outcome through common causes. In this note, we extend the discussion to scenarios where the selection is directly influenced by the outcome, but not by the exposure. We discuss whether these types of outcome-dependent selections preserve the sharp causal null hypothesis, and whether or not they allow for estimation of causal effects in the selected sample and/or in the source population.
在一篇具有开创性的论文中,埃尔南等人(2004年)针对选择是暴露因素与结果之间的对撞机的情况,对选择偏倚进行了系统分类。埃尔南(2017年)讨论了另一种情况,即选择在统计上与暴露因素无关,但通过共同原因与结果相关联。在本笔记中,我们将讨论扩展到选择直接受结果影响但不受暴露因素影响的情况。我们讨论了这些类型的结果依赖性选择是否保留了严格的因果零假设,以及它们是否允许在所选样本和/或源人群中估计因果效应。