Bagrel A
Ann Biol Clin (Paris). 1978;36(4):383-8.
In 1960, Yalow and Berson opened the route to radioimmunoassay. Now the technic of radioimmunoassay requires apart from the use of artificial radioisotopes, a compulsory stage of separation of free and linked phases. The author has developed a technic in homogeneous phase "EMIT" which avoids the intermediate stage of separation. He gives here the principle, studies the various parameters of the method, shows the advantages and disadvantages and compares it with other technics and finally mentions future prospects.
1960年，雅洛和伯森开启了放射免疫分析之路。如今，放射免疫分析技术除了使用人工放射性同位素外，还需要一个分离游离相和结合相的强制步骤。作者开发了一种均相“酶扩大免疫测定技术（EMIT）”，避免了分离的中间步骤。他在此阐述了该技术的原理，研究了方法的各种参数，展示了其优缺点，并与其他技术进行了比较，最后提到了未来前景。
