Department of Chemical Engineering, McGill University, 3610 University Street, Wong Building, Room 4180, Montréal, QC, H3A 0C5, Canada.
Department of Chemistry and Biochemistry and Centre for NanoScience Research, 7141 Rue Sherbrooke Ouest, Concordia University, Montreal, QC, H4B 1R6, Canada.
Nanoscale. 2023 Feb 16;15(7):2997-3031. doi: 10.1039/d2nr05565a.
Halide perovskite nanocrystals (HPNCs) have emerged at the forefront of nanomaterials research over the past two decades. The physicochemical and optoelectronic properties of these inorganic semiconductor nanoparticles can be modulated through the introduction of various ligands. The use of biomolecules as ligands has been demonstrated to improve the stability, luminescence, conductivity and biocompatibility of HPNCs. The rapid advancement of this field relies on a strong understanding of how the structure and properties of biomolecules influences their interactions with HPNCs, as well as their potential to extend applications of HPNCs towards biological applications. This review addresses the role of several classes of biomolecules (amino acids, proteins, carbohydrates, nucleotides, .) that have shown promise for improving the performance of HPNCs and their potential applications. Specifically, we have reviewed the recent advances on incorporating biomolecules with HP nanomaterials on the formation, physicochemical properties, and stability of HP compounds. We have also shed light on the potential for using HPs in biological and environmental applications by compiling some recent of proof-of-concept demonstrations. Overall, this review aims to guide the field towards incorporating biomolecules into the next-generation of high-performance HPNCs for biological and environmental applications.
卤化物钙钛矿纳米晶体（HPNCs）在过去二十年中成为纳米材料研究的前沿。通过引入各种配体，可以调节这些无机半导体纳米粒子的物理化学和光电特性。已经证明，使用生物分子作为配体可以提高 HPNCs 的稳定性、发光性、导电性和生物相容性。该领域的快速发展依赖于对生物分子的结构和性质如何影响它们与 HPNCs 的相互作用以及它们在将 HPNCs 的应用扩展到生物应用方面的潜力有深入的了解。这篇综述讨论了几类生物分子（氨基酸、蛋白质、碳水化合物、核苷酸等）在提高 HPNCs 性能及其潜在应用方面的作用。具体来说，我们综述了在 HPNCs 与生物纳米材料的形成、物理化学性质和稳定性方面结合生物分子的最新进展。我们还通过编译一些最近的概念验证演示，阐明了 HPs 在生物和环境应用中的潜力。总的来说，本综述旨在指导该领域将生物分子纳入下一代用于生物和环境应用的高性能 HPNCs。
