地衣二醇 A-B，两种新的愈创木烷-倍半萜类化合物，来自培养的地衣共生真菌。
Diorygmones A-B, two new guaiane-sesquiterpenes from the cultured lichen mycobiont of .
机构信息
Faculty of Applied Technology, School of Technology, Van Lang University, Ho Chi Minh City, Vietnam.
Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.
出版信息
Nat Prod Res. 2024 Jul;38(13):2282-2287. doi: 10.1080/14786419.2023.2172007. Epub 2023 Feb 1.
is a native crustose-lichen in Vietnam. A mycobiont of this lichen was isolated, then cultivated. The present study described the isolation and structural elucidation of two new guaiane-type sesquiterpenes, namely diorygmones A-B. Their absolute chemical structures were elucidated by extensive 1D and 2D NMR analysis, high-resolution mass spectroscopy, electronic circular dichroism (ECD), and comparisons with the literatures. Compounds and were evaluated for cytotoxic activity against HepG2 cell line.
是越南本土的一种壳状地衣。从这种地衣中分离出了一个真菌共生体，然后进行了培养。本研究描述了两种新的愈创木烷型倍半萜的分离和结构阐明，即二氧云母 A-B。通过广泛的 1D 和 2D NMR 分析、高分辨率质谱、电子圆二色性（ECD）以及与文献的比较，确定了它们的绝对化学结构。对 和 进行了抗 HepG2 细胞系的细胞毒性活性评价。
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