Danielsen Maria, Pallesen Kristine, Riber-Hansen Rikke, Bregnhøj Anne
Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
Department of Pathology, Aarhus University Hospital, Aarhus, Denmark.
Case Rep Dermatol. 2023 Jan 27;15(1):26-30. doi: 10.1159/000528422. eCollection 2023 Jan-Apr.
Prurigo pigmentosa (PP) is probably underdiagnosed due to lack of awareness. Previously, it was assumed that PP primarily affected Japanese females; however, more cases are reported worldwide, and the pathogenesis is still not completely understood. In this case report, we present two healthy Danish siblings, who developed PP approximately 2 weeks after starting a ketogenic diet, suggesting that both increased levels of ketone bodies in the blood together with a genetic predisposition might play a role in the development of PP.
色素性痒疹（PP）可能因认识不足而诊断不足。以前，人们认为PP主要影响日本女性；然而，世界各地报告的病例越来越多，其发病机制仍未完全明了。在本病例报告中，我们介绍了两名健康的丹麦同胞，他们在开始生酮饮食约2周后患上了PP，这表明血液中酮体水平升高以及遗传易感性可能在PP的发病过程中起作用。
