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伊朗一对兄妹夫妻患色素性痒疹的罕见病例。

A Rare Case of Prurigo Pigmentosa in Iranian Sibling Couple.

作者信息

Al-Zahawi Saman, Saberi Fatemeh, Azhari Vahidesadat, Kamyab Kambiz, Balighi Kamran

机构信息

Department of Dermatology Razi Hospital, Tehran University of Medical Sciences (TUMS) Tehran Iran.

Autoimmune Bullous Diseases Research Center Razi Hospital, Tehran University of Medical Sciences Tehran Iran.

出版信息

Clin Case Rep. 2025 Jan 16;13(1):e70121. doi: 10.1002/ccr3.70121. eCollection 2025 Jan.

DOI:10.1002/ccr3.70121
PMID:39831138
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11738638/
Abstract

Prurigo Pigmentosa is a rare inflammatory skin disease of unknown origin, characterized by pruritic, erythematous papules on the chest, back, neck, and anterior abdomen. The eruption resolves with reticular hyperpigmentation that cosmetically affects the patient's quality of life. Previous reports highlighted the role of the Ketogenic diet in triggering the disease in young female patients, however, no study reported the occurrence of Prurigo Pigmentosa in siblings of one family, unrelated to a ketogenic diet. Here, we report two sisters diagnosed with Prurigo Pigmentosa without undergoing a Ketogenic diet.

摘要

色素性痒疹是一种病因不明的罕见炎症性皮肤病，其特征为胸部、背部、颈部和前腹部出现瘙痒性红斑丘疹。皮疹消退后会留下网状色素沉着，这在外观上影响患者的生活质量。既往报道强调了生酮饮食在年轻女性患者中引发该病的作用，然而，尚无研究报道过一个家族中与生酮饮食无关的兄弟姐妹发生色素性痒疹的情况。在此，我们报告两姐妹被诊断为色素性痒疹，她们并未采用生酮饮食。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f922/11738638/9ae94f620a9d/CCR3-13-e70121-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f922/11738638/d2e64095634c/CCR3-13-e70121-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f922/11738638/328b1ece71b9/CCR3-13-e70121-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f922/11738638/0b7cfd70ecff/CCR3-13-e70121-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f922/11738638/fda41c9fa7d4/CCR3-13-e70121-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f922/11738638/00480ba7b635/CCR3-13-e70121-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f922/11738638/9ae94f620a9d/CCR3-13-e70121-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f922/11738638/d2e64095634c/CCR3-13-e70121-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f922/11738638/328b1ece71b9/CCR3-13-e70121-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f922/11738638/0b7cfd70ecff/CCR3-13-e70121-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f922/11738638/fda41c9fa7d4/CCR3-13-e70121-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f922/11738638/00480ba7b635/CCR3-13-e70121-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f922/11738638/9ae94f620a9d/CCR3-13-e70121-g007.jpg

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本文引用的文献

1
Clinical and Pathological Spectrum of Prurigo Pigmentosa in Central European Individuals.中欧人群痒疹性色素沉着症的临床和病理谱。
JAMA Dermatol. 2023 Aug 1;159(8):864-869. doi: 10.1001/jamadermatol.2023.1917.
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Prurigo Pigmentosa Induced by a Ketogenic Diet.生酮饮食诱发的色素性痒疹。
Cureus. 2023 May 25;15(5):e39498. doi: 10.7759/cureus.39498. eCollection 2023 May.
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Confluent and reticulated papillomatosis, prurigo pigmentosa, and antibiotic preference.融合性网状乳头瘤病、色素性痒疹与抗生素偏好
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A Rare Case of Prurigo Pigmentosa in a Danish Sibling Couple.丹麦一对兄弟姐妹夫妇患色素性痒疹的罕见病例。
Case Rep Dermatol. 2023 Jan 27;15(1):26-30. doi: 10.1159/000528422. eCollection 2023 Jan-Apr.
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Clinical Features and Follow-Up of Prurigo Pigmentosa: A Case Series.色素性痒疹的临床特征及随访：病例系列报道
Cureus. 2022 Apr 29;14(4):e24600. doi: 10.7759/cureus.24600. eCollection 2022 Apr.
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Clinical manifestations and treatment outcomes in prurigo pigmentosa (Nagashima disease): A systematic review of the literature.色素性痒疹（长岛病）的临床表现及治疗结果：文献系统综述
JAAD Int. 2021 Apr 10;3:79-87. doi: 10.1016/j.jdin.2021.03.003. eCollection 2021 Jun.
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Prurigo pigmentosa and new-onset type 1 diabetes in a black female patient testing positive for SARS-CoV-2 IgG.一名SARS-CoV-2 IgG检测呈阳性的黑人女性患者出现色素性痒疹和新发1型糖尿病。
Br J Dermatol. 2021 Jan;184(1):e5. doi: 10.1111/bjd.19568. Epub 2020 Oct 25.
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Prurigo Pigmentosa: A Clinicopathological Report of Three Middle Eastern Patients.色素性痒疹：3例中东患者的临床病理报告
Case Rep Dermatol Med. 2018 Jul 9;2018:9406797. doi: 10.1155/2018/9406797. eCollection 2018.
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Prurigo Pigmentosa in White Monozygotic Twins.白色单卵双胞胎中的色素性痒疹。
JAMA Dermatol. 2017 Mar 1;153(3):353-354. doi: 10.1001/jamadermatol.2016.4921.
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Segmental prurigo pigmentosa.节段性色素性痒疹
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