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一例罕见的蜡样芽孢杆菌性化脓性关节炎病例。

A Rare Case of Bacillus cereus Septic Arthritis.

作者信息

Newman Peter, Garcia Monica, Ward Rebecca, Killian John, Mayberry Sharon

机构信息

Pediatric Residency, University of Florida College of Medicine, Pensacola, USA.

Pediatric Hospitalist, University of Florida College of Medicine, Pensacola, USA.

出版信息

Cureus. 2022 Dec 30;14(12):e33148. doi: 10.7759/cureus.33148. eCollection 2022 Dec.

DOI:10.7759/cureus.33148
PMID:36726927
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9884740/
Abstract

Joint infections are rare in pediatrics, and those caused by are practically unheard of. In this case report, we examine a singular case of septic arthritis in a child, with the purpose of educating clinicians on the presentation, inpatient and outpatient management, and clinical outcome. We report the case of a previously healthy pediatric patient who presented to the emergency department with symptoms of septic arthritis of the left knee. The orthopedics team performed arthroscopy and debridement, and the synovial fluid culture grew . To our knowledge, this is the first case report on septic arthritis caused by in the pediatric population. The treatment protocol consisted of intravenous vancomycin for one week, followed by three weeks of oral ciprofloxacin therapy. The patient had an excellent clinical outcome and returned to normal mobility without limitations. Despite being ubiquitous in the environment, extra-intestinal infection is exceedingly rare in immunocompetent individuals. It is so rare, in fact, that it is often dismissed as a lab contaminant. In this case, we demonstrated that cooperation between multiple disciplines offers good clinical outcomes for rare infections, especially those in pediatrics.

摘要

关节感染在儿科中很少见,而由[未提及具体病菌名称]引起的关节感染几乎闻所未闻。在本病例报告中,我们研究了一例儿童脓毒性关节炎的独特病例,目的是让临床医生了解其临床表现、住院和门诊管理以及临床结局。我们报告了一例既往健康的儿科患者,该患者因左膝脓毒性关节炎症状就诊于急诊科。骨科团队进行了关节镜检查和清创术,滑膜液培养结果为[未提及具体病菌名称]。据我们所知,这是儿科人群中首例由[未提及具体病菌名称]引起的脓毒性关节炎病例报告。治疗方案包括静脉注射万古霉素一周,随后口服环丙沙星治疗三周。患者临床结局良好,恢复正常活动,无活动受限。尽管[未提及具体病菌名称]在环境中普遍存在,但在免疫功能正常的个体中,肠外[未提及具体病菌名称]感染极为罕见。事实上,它非常罕见,以至于常被当作实验室污染物而不予理会。在本病例中,我们证明了多学科之间的合作可为罕见感染,尤其是儿科罕见感染带来良好的临床结局。

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Post-procedural septic arthritis in a patient with systemic lupus erythematosus.系统性红斑狼疮患者术后感染性关节炎
Afr J Lab Med. 2020 Aug 20;9(1):1119. doi: 10.4102/ajlm.v9i1.1119. eCollection 2020.
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Septic arthritis in children: Updated epidemiologic, microbiologic, clinical and therapeutic correlations.儿童脓毒性关节炎:最新的流行病学、微生物学、临床和治疗相关性。
Pediatr Neonatol. 2020 Jun;61(3):325-330. doi: 10.1016/j.pedneo.2020.02.006. Epub 2020 Feb 22.
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Septic arthritis in children: diagnosis and treatment.儿童化脓性关节炎:诊断与治疗
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