College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.
Chem Soc Rev. 2023 Feb 20;52(4):1168-1188. doi: 10.1039/d3cs00009e.
Organic electrosynthesis is a green strategy for the synthesis of valuable molecules. Electrochemical reactions using sacrificial metal anodes enable new reactivity to be uncovered that could not be achieved with traditional non-electrochemical methods. Compared with reactions using metal powder as the reducing reagent, the mild electroreduction protocols usually exhibit diverse reactivity and excellent selectivity. The inexpensive metal anodes possess low oxidation potential, which could prevent undesired overoxidation of substrates, active intermediates and products. The generated metal ions from sacrificial anodes could not only serve as Lewis acids to activate the reactants but also as a promoter or mediator. This tutorial review highlights the recent achievements in this rapidly growing area within the past five years. The sacrificial anode-enabled electroreductions are discussed according to the reaction type.
有机电化学合成是一种绿色的策略，用于合成有价值的分子。使用牺牲性金属阳极的电化学反应能够揭示新的反应性，这是传统的非电化学方法所无法实现的。与使用金属粉末作为还原剂的反应相比，温和的电还原方案通常表现出多样的反应性和优异的选择性。廉价的金属阳极具有低氧化电位，可防止底物、活性中间体和产物的不必要的过度氧化。牺牲性阳极产生的金属离子不仅可以作为路易斯酸来激活反应物，还可以作为促进剂或介体。本综述重点介绍了过去五年中这一快速发展领域的最新成就。根据反应类型讨论了牺牲阳极促进的电还原。
