Human Performance Research Laboratory, Department of Kinesiology, University of North Alabama, Florence, Alabama; and.
Metabolic & Applied Physiology Laboratory, Department of Health and Human Performance, Texas State University, San Marcos, Texas.
J Strength Cond Res. 2023 Jul 1;37(7):e413-e421. doi: 10.1519/JSC.0000000000004408. Epub 2023 Jan 18.
Waldman, HS, Bryant, AR, Parten, AL, Grozier, CD, and McAllister, MJ. Astaxanthin supplementation does not affect markers of muscle damage or inflammation after an exercise-induced muscle damage protocol in resistance-trained males. J Strength Cond Res 37(7): e413-e421, 2023-It is well documented that exercise-induced muscle damage (EIMD) decreases exercise performance by elevated inflammation and subjective discomfort. Due to its potent antioxidative properties, astaxanthin (AX) may serve as a potential dietary supplement strategy for mitigating delayed-onset muscle soreness (DOMS) and enhancing recovery and performance. This study aimed to investigate the effects of AX on markers of muscle damage, inflammation, DOMS, and anaerobic performance and substrate metabolism. Thirteen resistance-trained men (mean ± SD , age, 23.4 ± 2.1 years) completed a double-blind, counterbalanced, and crossover design with a 1-week washout period between 2, 4-week supplementation periods at 12 mg·d -1 of AX or placebo. After each supplementation period, subjects completed 2 trials, with trial 1 including a graded exercise test (GXT) and a 30-second Wingate and trial 2 including an EIMD protocol followed by the collection of fasting blood samples (pre-post) to measure creatine kinase, advanced oxidative protein products, C-reactive protein, interleukin-6, insulin, and cortisol. Astaxanthin supplementation had no statistical effects on markers of substrate metabolism during the GXT, Wingate variables, or markers of muscle damage, inflammation, or DOMS when compared with placebo (all p > 0.05). However, 4 weeks of AX supplementation did significantly lower oxygen consumption during the final stage of the GXT (12%, p = 0.02), as well as lowered systolic blood pressure (∼7%, p = 0.04), and significantly lowered baseline insulin values (∼24%, p = 0.05) when compared with placebo. Collectively, these data suggest that 4 weeks of AX supplementation at 12 mg·d -1 did not affect markers of muscle damage, inflammation, or DOMS after an EIMD protocol in a resistance-trained male cohort.
沃尔德曼、布莱恩特、帕特恩、格罗泽、麦卡利斯特。虾青素补充剂不会影响阻力训练男性运动引起的肌肉损伤后肌肉损伤和炎症的标志物。J 力量与调节研究 37(7)：e413-e421，2023 年-运动引起的肌肉损伤 (EIMD) 通过增加炎症和主观不适降低运动表现，这是有充分文献记载的。由于其强大的抗氧化特性，虾青素 (AX) 可能是一种潜在的膳食补充策略，可以减轻延迟性肌肉酸痛 (DOMS) 并增强恢复和表现。本研究旨在研究 AX 对肌肉损伤、炎症、DOMS 和无氧性能和底物代谢标志物的影响。13 名阻力训练男性（平均±标准差，年龄 23.4±2.1 岁）完成了一项双盲、交叉设计的研究，2 周洗脱期，4 周补充期，分别补充 12 毫克/天的 AX 或安慰剂。在每个补充期后，受试者完成 2 次试验，试验 1 包括递增运动测试 (GXT) 和 30 秒的仰卧起坐和试验 2 包括运动引起的肌肉损伤协议，然后采集空腹血样（前后）测量肌酸激酶、高级氧化蛋白产物、C-反应蛋白、白细胞介素-6、胰岛素和皮质醇。与安慰剂相比，AX 补充剂对 GXT 期间的底物代谢标志物、仰卧起坐变量或肌肉损伤、炎症或 DOMS 标志物均无统计学影响（均 p>0.05）。然而，4 周的 AX 补充剂显著降低了 GXT 最后阶段的耗氧量（12%，p=0.02），以及降低了收缩压（7%，p=0.04），并显著降低了基线胰岛素值（24%，p=0.05），与安慰剂相比。总的来说，这些数据表明，在阻力训练男性队列中，4 周补充 12 毫克/天的 AX 不会影响 EIMD 方案后的肌肉损伤、炎症或 DOMS 标志物。
