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[Au(N^N)Br](PF6):一类具有抗菌和抗生物膜特性的配合物(N^N = 2,2'-联吡啶和 1,10-菲啰啉衍生物)。

[Au(N^N)Br](PF): A Class of Antibacterial and Antibiofilm Complexes (N^N = 2,2'-Bipyridine and 1,10-Phenanthroline Derivatives).

机构信息

Dipartimento di Scienze Chimiche e Geologiche, Università degli Studi di Cagliari, S. S. 554 bivio per Sestu, Monserrato Cagliari09042, Italy.

Centro Servizi di Ateneo per la Ricerca (CeSAR), Università degli Studi di Cagliari, S. S. 554 bivio per Sestu, Monserrato Cagliari09042, Italy.

出版信息

Inorg Chem. 2023 Feb 13;62(6):2924-2933. doi: 10.1021/acs.inorgchem.2c04410. Epub 2023 Feb 2.

Abstract

A series of new complexes of general formula Au(N^N)Br (N^N = 2,2'-bipyridine and 1,10-phenanthroline derivatives) were prepared and characterized by spectroscopic, electrochemical, and diffractometric techniques and tested against Gram-positive and Gram-negative bacterial strains (, , , and ), showing promising antibacterial and antibiofilm properties.

摘要

一系列新的Au(N^N)Br(N^N = 2,2'-联吡啶和 1,10-菲咯啉衍生物)配合物通过光谱、电化学和衍射技术进行了制备和表征,并针对革兰氏阳性和革兰氏阴性细菌菌株( , , , )进行了测试,显示出有希望的抗菌和抗生物膜特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b266/9930124/760af76bf0b2/ic2c04410_0006.jpg

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