Center of Excellence in Women & Child Health, The Aga Khan University, Pakistan.
Biostat Global Consulting, Worthington, OH.
Pediatr Infect Dis J. 2023 Mar 1;42(3):260-270. doi: 10.1097/INF.0000000000003804. Epub 2023 Jan 2.
Immunization is one of the most successful public health interventions available, saving millions of lives from death and disability each year. Therefore, improving immunization coverage is a high priority for the Government of Pakistan and essential to progress toward universal health coverage. This survey reports the national and provincial/regional coverage and determinants of fully, partially, and not-vaccinated children 12-23 months of age, antigen-wise coverage, percentage of home-based vaccination records (HBR) retention, and reasons for nonretention; dropout, timeliness, and prevalence of missed opportunities for simultaneous vaccination (MOSV).
The survey was a descriptive cross-sectional national household survey carried out across Pakistan. The survey included 110,790 children 12-23 months old and their caregivers. A World Health Organization (WHO)-Expanded Program on Immunization (EPI) Survey questionnaire was adapted to collect information. Data were analyzed using the WHO Vaccination Coverage Quality Indicators (VCQI) software and Stata version 17.
Nationally excluding Azad Jammu and Kashmir (AJK) and Gilgit Baltistan (GB), the coverage of fully vaccinated children was 76.5%. The likelihood of being fully vaccinated was higher among children of educated parents who belonged to higher wealth quintiles and resided in any province/region other than Balochistan. The main reasons for unimmunization were no faith in immunization, rumors about vaccines, and distance to the facility. About two-thirds (66.2%) of the children had their HBR available, and the main reasons for not having a card were never visiting a health facility and having no awareness about the importance of a card. Dropout was discernible for later doses of vaccines compared with earlier ones. Higher proportions of children received the last doses late by more than two months. Of the 218,002 vaccination visits documented on HBR in the provinces, MOSVs occurred in 17.6% of the visits.
The immunization coverage rates provide a direction to strategize the progress to improve the vaccination rates in Pakistan. The country needs to outline the immediate and long-term actions to combat vaccine-preventable diseases, such as escalating integrated immunization campaigns and outreach activities, provision of mobility support, and deploying behavioral interventions as a cross-cutting strategy to improve awareness and reduce misconceptions.
免疫接种是现有最成功的公共卫生干预措施之一,每年使数百万人免于死亡和残疾。因此,提高免疫接种覆盖率是巴基斯坦政府的当务之急,也是实现全民健康覆盖的关键。本调查报告了全国和省级/地区 12-23 个月龄完全、部分和未接种儿童的覆盖率以及决定因素,抗原覆盖率,家庭为基础的疫苗接种记录(HBR)保留率,以及不保留的原因;辍学、及时性以及同时接种(MOSV)机会缺失的流行率。
该调查是在巴基斯坦全国范围内进行的一项描述性横断面家庭调查。该调查包括 110790 名 12-23 个月大的儿童及其照顾者。采用世界卫生组织(WHO)扩大免疫规划(EPI)调查问卷收集信息。使用世界卫生组织疫苗接种覆盖率质量指标(VCQI)软件和 Stata 版本 17 进行数据分析。
在不包括阿扎德查谟和克什米尔(AJK)和吉尔吉特-巴尔蒂斯坦(GB)的情况下,全国完全接种疫苗的儿童覆盖率为 76.5%。受教育程度较高的父母的孩子、属于较高财富五分位数的孩子以及居住在除俾路支省以外的任何省份/地区的孩子,其完全接种疫苗的可能性更高。未免疫的主要原因是对免疫没有信心、对疫苗的谣言以及距离接种点的距离。约三分之二(66.2%)的儿童有 HBR 可用,没有 HBR 的主要原因是从未去过卫生机构,并且不知道 HBR 的重要性。与早期疫苗相比,后期疫苗的接种率更高。在记录于 HBR 的 218002 次接种访问中,有 17.6%的访问发生了 MOSV。
免疫接种覆盖率为巴基斯坦制定提高疫苗接种率的战略提供了方向。该国需要制定近期和长期行动,以应对疫苗可预防疾病,例如加强综合免疫运动和外联活动、提供流动支持以及部署行为干预措施作为一项交叉策略,以提高认识并减少误解。