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在 Raystation 中使用脚本实现自动化个体化乳腺癌放射治疗计划技术。

Implementation of automated personalised breast radiotherapy planning techniques with scripting in Raystation.

机构信息

Department of Medical Physics, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, UK.

出版信息

Br J Radiol. 2023 Mar 1;96(1144):20220707. doi: 10.1259/bjr.20220707. Epub 2023 Feb 20.

Abstract

OBJECTIVE

Implement scripted automatic breast planning (AP) for breast techniques within Raystation.

METHODS

Manual plans (MPs) were re-planned and compared with AP plans for whole breast (WB), partial breast (PB), hybrid volumetric modulated arc therapy simultaneous integrated boost (VMAT SIB) and VMAT nodal plans.

RESULTS

WB AP plans took 7 min comparing well to MP. One WB AP failed a mandatory dose constraint. Small statistically significant differences showed improved coverage for AP at expense of slightly hotter plans, however absolute differences were small (mean differences < 1% or D <0.2 Gy). PB AP plans took 9 min, showing improved coverage (V 97.6  96.4 %). One PB AP case failed a mandatory constraint. Other dosimetric differences were non-significant. SIB AP plans took 14 min with one case failing a mandatory constraint with minor differences compared with MP except larger V (3  1.5 %) and more MU. VMAT AP plans took 12 min and were hotter for PTVp_4000 but had higher nodal coverage. Contra_Lung V was higher (8.8 %) than MP plans (6.5 %).

CONCLUSION

Automatic planning of modern breast techniques has been successfully introduced using a commercial planning system. AP plans are very similar to MP, requiring little manual interaction for most cases with significant timesaving potential.

ADVANCES IN KNOWLEDGE

Scripted breast plans produced within minutes for WB, PB, SIB and VMAT. Successfully introduced into large busy department. Plans similar to manual plans, requiring little manual interaction.

摘要

目的

在 Raystation 中实现针对乳房技术的脚本化自动计划(AP)。

方法

对全乳(WB)、部分乳房(PB)、混合容积调强弧形治疗同步整合增敏(VMAT SIB)和 VMAT 淋巴结计划的手动计划(MP)进行重新计划,并与 AP 计划进行比较。

结果

WB AP 计划用时 7 分钟,与 MP 相比表现良好。一个 WB AP 计划未能满足强制性剂量限制。AP 计划在覆盖范围上有小的统计学显著改善,但代价是计划略热,然而绝对差异较小(平均差异<1%或 D<0.2Gy)。PB AP 计划用时 9 分钟,显示出覆盖范围的改善(V97.6>96.4%)。一个 PB AP 病例未能满足强制性限制。其他剂量学差异无统计学意义。SIB AP 计划用时 14 分钟,一个病例未能满足强制性限制,与 MP 相比,除了 V(3 1.5%)和 MU 更多外,差异较小。VMAT AP 计划用时 12 分钟,PTVp_4000 处较热,但淋巴结覆盖更高。对照肺 V(8.8%)高于 MP 计划(6.5%)。

结论

使用商业计划系统成功地引入了现代乳房技术的自动计划。AP 计划与 MP 非常相似,对于大多数病例只需很少的手动交互,具有显著的节省时间的潜力。

知识进展

数分钟内为 WB、PB、SIB 和 VMAT 生成脚本化乳房计划。成功引入大型繁忙科室。计划与手动计划相似,需要很少的手动交互。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38cf/10078863/1f4473011b9a/bjr.20220707.g001.jpg

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