Department of Diagnostic Imaging, Sheba Medical Center, Tel Hashomer, Israel, affiliated with the Sackler School of Medicine, Tel Aviv University, Tel-Aviv, Israel.
Department of Radiology (CCM), Charité - Universitätsmedizin Berlin, Campus Mitte, Humboldt-Universität Zu Berlin, Freie Universität Berlin, Charitéplatz 1, Berlin, Germany.
Curr Opin Rheumatol. 2023 Jul 1;35(4):219-225. doi: 10.1097/BOR.0000000000000925. Epub 2022 Dec 27.
Pelvic radiography in which structural lesions characteristic of sacroiliitis can be detected, is recommended as the first imaging modality when axial spondyloarthritis (axSpA) is suspected clinically. However, cross-sectional modalities like computed tomography (CT) and magnetic resonance imaging (MRI) are superior to radiographs for diagnosing sacroiliitis. Thus, we currently debate the role of radiography as first imaging modality in the diagnostic workup of axSpA.
Diagnosing sacroiliitis on pelvic radiographs is challenging with large interobserver and intraobserver variation. Low-dose CT (ldCT) of the sacroiliac joints (SIJs) was proved to be more sensitive and reliable than radiographs with comparable ionizing radiation exposure. MRI is the preferred modality for detecting early SIJ inflammation, well before structural lesions evolve. New, promising MRI sequences sensitive to cortical bone improve erosion detection, making MRI a one-stop shop for the diagnosis of sacroiliitis.
Given the debatable additive value of pelvic radiographs for the detection of sacroiliitis, and the presence of excellent alternatives for imaging the bony cortex of the SIJs such as ldCT and MRI with state-of-the-art sequences sensitive to cortical bone, it is high time to discuss the use of these more accurate modalities instead of radiographs.
当临床怀疑存在中轴型脊柱关节炎(axSpA)时,建议首先进行影像学检查,以发现具有特征性骶髂关节炎结构病变的骨盆 X 射线摄影。然而,与 X 射线相比,横断面成像方式(如计算机断层扫描[CT]和磁共振成像[MRI])在诊断骶髂关节炎方面更具优势。因此,我们目前正在争论 X 射线摄影作为 axSpA 诊断评估的初始影像学检查方法的作用。
在 X 射线摄影上诊断骶髂关节炎具有较大的观察者间和观察者内差异,具有挑战性。与 X 射线相比,骶髂关节低剂量 CT(ldCT)具有相似的电离辐射暴露,其具有更高的敏感性和可靠性。MRI 是检测早期骶髂关节炎症的首选方法,在结构病变出现之前就可以很好地进行检测。新的、有前途的、对皮质骨敏感的 MRI 序列可提高侵蚀检测的灵敏度,使 MRI 成为诊断骶髂关节炎的一站式方法。
鉴于骨盆 X 射线摄影对骶髂关节炎检测的附加价值存在争议,并且存在 ldCT 和 MRI 等用于成像骶髂关节骨皮质的极好替代方法,这些方法具有最新的、对皮质骨敏感的序列,因此,是时候讨论使用这些更准确的方法来替代 X 射线摄影了。