From the Department of Health Economics and Health Systems Innovations, National Institute of Public Health of Mexico, Cuernavaca, Morelos, México.
Sex Transm Dis. 2023 Aug 1;50(8):512-517. doi: 10.1097/OLQ.0000000000001759. Epub 2022 Dec 21.
This article describes perceptions and experiences related to the preexposure prophylaxis (PrEP) care continuum of Mexican men who have sex with men (MSM) and transwomen (TW).
Between June and July 2020, we applied 24 online semistructured interviews regarding PrEP use with 10 PrEP users, 6 ex-users, and 8 potential users (at risk, not enrolled).
Awareness: TW did not always receive the information they needed from trusted people. Acceptability: Potential users were reluctant to use PrEP because of fear of adverse effects, and only a few participants worried about stigma. Uptake: Potential users missed their enrollment visit and did not know how to reschedule. Adherence: Barriers included routine changes interfering with PrEP-taking habits (arriving home later, traveling, etc.), whereas feeling protected was reported as a facilitator. Retention: Ex-users quit PrEP services, mostly without reducing their HIV risk, because of difficulties keeping appointments and fearing long-term effects.
Inclusive awareness activities, tackling misbeliefs regarding adverse effects, and more flexible services may improve PrEP usage and enhance its impact.
本文描述了墨西哥男男性行为者和跨性别女性（TW）对暴露前预防（PrEP）护理连续体的看法和体验。
2020 年 6 月至 7 月期间，我们对 10 名 PrEP 使用者、6 名前使用者和 8 名潜在使用者（有风险但未登记）进行了 24 次有关 PrEP 使用的在线半结构式访谈。
意识：TW 并不总是从可信赖的人那里获得他们需要的信息。可接受性：潜在使用者因担心副作用而不愿意使用 PrEP，只有少数参与者担心污名化。接受：潜在使用者错过了他们的登记访问，不知道如何重新安排。坚持：日常变化干扰了 PrEP 的服用习惯（回家较晚、旅行等）被认为是一个障碍，而感到受保护则被认为是一个促进因素。保留：前使用者停止使用 PrEP 服务，主要是因为难以预约和担心长期影响，而没有降低他们的 HIV 风险。
开展包容意识活动、解决对副作用的误解以及提供更灵活的服务，可能会提高 PrEP 的使用率并增强其影响。
