Koh Shizuka, Inoue Ryota, Iwamoto Yuuri, Mihashi Toshifumi, Soma Takeshi, Maeda Naoyuki, Nishida Kohji
Department of Innovative Visual Science (S.K., R.I.), Osaka University Graduate School of Medicine, Osaka, Japan; Department of Ophthalmology (S.K., Y.I., T.S., K.N.), Osaka University Graduate School of Medicine, Osaka, Japan; SEED CO. (R.I.), LTD., Tokyo, Japan; and Department of Orthoptics (T.M.), Faculty of Medical Technology, Teikyo University, Tokyo, Japan.
Eye Contact Lens. 2023 Mar 1;49(3):98-103. doi: 10.1097/ICL.0000000000000965. Epub 2022 Dec 20.
To assess agreement between measurements of ocular wavefront aberrations obtained using the Pentacam AXL Wave (Oculus Optikgeräte GmbH) (Aberrometer A) and KR-1W (Topcon Corp) (Aberrometer B), both of which are based on the Hartmann-Shack principle.
In this prospective case-control study, ocular wavefront aberrations measurements were obtained using both aberrometers in patients with keratoconus (KC) and control participants. Ocular wavefront aberrations were measured through the natural pupil without dilation using both devices in a dark room. For both aberrometers, accommodation was inhibited by automatically adding fogging. The individual Zernike coefficients from the second to fourth order were compared between the two aberrometers for a 4-mm pupil diameter.
Twenty-six KC and 29 control eyes were assessed. Statistically significant correlations ( P <0.05) were observed for all Zernike coefficients, except for Z 4-2 in the control group. Bland-Altman analysis indicated good agreement between aberrometers and no statistically significant differences in the control group. However, in the KC group, patterns of proportional error were observed in vertical coma Z 3-1 (r=0.338, P =0.008), trefoil Z 4-4 (r=0.701, P =0.003), secondary astigmatism Z 4-2 (r=0.348, P =0.025), and spherical aberrations Z 40 (r=0.407, P =0.012).
The Zernike coefficient values measured by the two aberrometers were well correlated in the control and KC groups. However, in eyes with KC, Aberrometer B tended to present greater values in several Zernike coefficients than Aberrometer A, suggesting that wavefront measurements obtained using the two aberrometers are not interchangeable in patients with KC.
评估使用基于哈特曼-夏克原理的Pentacam AXL Wave（奥culus光学设备有限公司）（像差仪A）和KR-1W（拓普康公司）（像差仪B）获得的眼波前像差测量值之间的一致性。
在这项前瞻性病例对照研究中，使用这两种像差仪对圆锥角膜（KC）患者和对照参与者进行眼波前像差测量。在暗室中，使用这两种设备通过自然瞳孔且不进行散瞳来测量眼波前像差。对于这两种像差仪，通过自动添加雾视来抑制调节。比较两种像差仪在4毫米瞳孔直径下从二阶到四阶的各个泽尼克系数。
评估了26只KC眼和29只对照眼。除对照组中的Z4-2外，所有泽尼克系数均观察到具有统计学意义的相关性（P<0.05）。布兰德-奥特曼分析表明像差仪之间具有良好的一致性，且对照组中无统计学显著差异。然而，在KC组中，在垂直彗差Z3-1（r=0.338，P=0.008）、三叶草像差Z4-4（r=0.701，P=0.003）、继发性散光Z4-2（r=0.348，P=0.025）和球差Z40（r=0.407，P=0.012）中观察到比例误差模式。
两种像差仪测量的泽尼克系数值在对照组和KC组中具有良好的相关性。然而，在KC眼中，像差仪B在几个泽尼克系数上的值往往比像差仪A更大，这表明在KC患者中，使用这两种像差仪获得的波前测量值不可互换。
