• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

慢性眼表疼痛的新疗法。

Novel Treatments for Chronic Ocular Surface Pain.

机构信息

Surgical Services, Miami Veterans Affairs Medical Center, Miami, FL; and.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL.

出版信息

Cornea. 2023 Mar 1;42(3):261-271. doi: 10.1097/ICO.0000000000003193. Epub 2022 Dec 19.

DOI:10.1097/ICO.0000000000003193
PMID:36729473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9918665/
Abstract

Several etiologies can contribute to ocular surface pain including nociceptive, peripheral neuropathic, and central neuropathic mechanisms. Clinical clues can help identify contributors to ocular surface pain in a patient. In individuals whose pain persists despite targeting nociceptive contributors, neuropathic mechanisms should be considered and addressed using oral, topical, and/or adjuvant agents.

摘要

几种病因可导致眼表面疼痛,包括伤害感受性、周围神经性和中枢神经性机制。临床线索有助于识别患者眼表面疼痛的病因。对于那些尽管针对伤害感受性病因进行治疗但疼痛仍持续存在的个体,应考虑神经病理性机制,并使用口服、局部和/或辅助药物进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d7/9918665/9053035b5c3f/nihms-1839866-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d7/9918665/323136ab04e1/nihms-1839866-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d7/9918665/6a9a4c8d71ed/nihms-1839866-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d7/9918665/9053035b5c3f/nihms-1839866-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d7/9918665/323136ab04e1/nihms-1839866-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d7/9918665/6a9a4c8d71ed/nihms-1839866-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d7/9918665/9053035b5c3f/nihms-1839866-f0003.jpg

相似文献

1
Novel Treatments for Chronic Ocular Surface Pain.慢性眼表疼痛的新疗法。
Cornea. 2023 Mar 1;42(3):261-271. doi: 10.1097/ICO.0000000000003193. Epub 2022 Dec 19.
2
A Review of Management Strategies for Nociceptive and Neuropathic Ocular Surface Pain.眼表痛觉和神经病理性疼痛的管理策略综述。
Drugs. 2020 Apr;80(6):547-571. doi: 10.1007/s40265-020-01282-3.
3
Incomplete response to artificial tears is associated with features of neuropathic ocular pain.对人工泪液反应不完全与神经性眼痛的特征相关。
Br J Ophthalmol. 2016 Jun;100(6):745-9. doi: 10.1136/bjophthalmol-2015-307094. Epub 2015 Sep 16.
4
Neuropathic ocular surface pain: Emerging drug targets and therapeutic implications.神经病理性眼表疼痛:新兴的药物靶点和治疗意义。
Expert Opin Ther Targets. 2022 Aug;26(8):681-695. doi: 10.1080/14728222.2022.2122438. Epub 2022 Sep 20.
5
Ocular surface itch and pain: key differences and similarities between the two sensations.眼表痒和痛:两种感觉的关键差异和相似之处。
Curr Opin Allergy Clin Immunol. 2023 Oct 1;23(5):415-422. doi: 10.1097/ACI.0000000000000934. Epub 2023 Jul 24.
6
Neuropathic ocular pain: an important yet underevaluated feature of dry eye.神经性眼痛:干眼的一个重要但未得到充分评估的特征。
Eye (Lond). 2015 Mar;29(3):301-12. doi: 10.1038/eye.2014.263. Epub 2014 Nov 7.
7
Evidence of central sensitisation in those with dry eye symptoms and neuropathic-like ocular pain complaints: incomplete response to topical anaesthesia and generalised heightened sensitivity to evoked pain.患有干眼症状和神经性眼痛主诉者的中枢敏化证据:对局部麻醉反应不完全以及对诱发性疼痛的全身性敏感性增强。
Br J Ophthalmol. 2017 Sep;101(9):1238-1243. doi: 10.1136/bjophthalmol-2016-309658. Epub 2017 Jan 18.
8
Management of Ocular Neuropathic Pain With Vitamin B12 Supplements: A Case Report.维生素B12补充剂治疗眼部神经性疼痛:一例报告
Cornea. 2015 Oct;34(10):1324-5. doi: 10.1097/ICO.0000000000000572.
9
Neuropathic corneal pain and dry eye: a continuum of nociception.神经病理性角膜痛和干眼:痛觉传导的连续统一体。
Br J Ophthalmol. 2022 Aug;106(8):1039-1043. doi: 10.1136/bjophthalmol-2020-318469. Epub 2021 Apr 30.
10
Differentiating primary dry eye disease from ocular neuropathic pain: implications for symptom management.区分原发性干燥性眼病和眼神经性疼痛:对症状管理的影响。
Clin Exp Optom. 2023 Aug;106(6):605-611. doi: 10.1080/08164622.2022.2111199. Epub 2022 Aug 25.

引用本文的文献

1
Chronic Ocular Surface Pain: An Optometrist and Ophthalmologist Survey.慢性眼表疼痛:验光师和眼科医生调查
Ophthalmol Ther. 2025 Sep 5. doi: 10.1007/s40123-025-01234-8.
2
Long-Term Evolution of Chronic Neuropathic Ocular Pain and Dry Eye Following Corneal Refractive Surgery.角膜屈光手术后慢性神经性眼痛和干眼的长期演变
J Clin Med. 2025 Jun 20;14(13):4406. doi: 10.3390/jcm14134406.
3
Validation of the Ocular Pain Assessment Survey Instrument With Rasch Analysis.使用拉施分析验证眼痛评估调查问卷工具
Transl Vis Sci Technol. 2025 Feb 3;14(2):20. doi: 10.1167/tvst.14.2.20.
4
CORONIS symposium 2023: Scientific and clinical frontiers in ocular surface innervation.2023年科罗尼斯研讨会:眼表神经支配的科学与临床前沿
Acta Ophthalmol. 2025 Jun;103(4):e240-e255. doi: 10.1111/aos.17450. Epub 2025 Jan 31.
5
Investigating recent advances in pharmacotherapy for acute and chronic ocular pain post-cataract surgery.探究白内障手术后急慢性眼痛药物治疗的最新进展。
Expert Opin Pharmacother. 2024 Nov;25(16):2107-2113. doi: 10.1080/14656566.2024.2421323. Epub 2024 Oct 28.
6
Rethinking Sjögren Beyond Inflammation: Considering the Role of Nerves in Driving Disease Manifestations.重新思考干燥综合征:关注神经在驱动疾病表现中的作用。
Eye Contact Lens. 2024 May 1;50(5):200-207. doi: 10.1097/ICL.0000000000001068. Epub 2024 Feb 7.