[The role of amino acids in the regulation of gastric secretion].

The experiments conducted on dogs have demonstrated that amino acids entering blood increase the maximum response of gastric glands to pentagastrin 2-3-fold, to histamine by 20-25%. The test on rats has revealed varying concentrations of amino acids when they are passing through the liver: a half of certain amino acids (lysine, glycine, proline etc.) is retained in the liver, other (cystine) increase their concentration in the hepatic vein as compared to that in the portal vein, whereas amino acids with ramified carbon chain are insignificantly retained by the liver. The data obtained have evidenced an important role of amino acids in the third intestinal phase of gastric secretion during protein food intake and in the modulating of gastric secretion under conditions of mixed food intake.