Laboratory of Neuroplasticity, Institute of Health Sciences, Federal University of Pará, Belém, Pará, Brazil.
Parkinson Group, Art Science Institute, Federal University of Pará, Belém, Pará, Brazil.
PLoS One. 2023 Feb 2;18(2):e0281204. doi: 10.1371/journal.pone.0281204. eCollection 2023.
Parkinson's disease (PD) is a progressive, neurodegenerative disease with motor symptoms that are well understood, but non-motor symptoms may be present and appear at different temporal stages of the disease. Physical activity based on dance movements is emerging as a complementary therapeutic approach to a range of PD symptoms as a multidimensional activity that requires rhythmic synchronization and more neuromuscular functions.
To evaluate the effects of physical activity based on dance movements on the movement, executive functions, depressive symptoms, quality of life, and severity of PD in individuals diagnosed with PD.
13 individuals with PD (Hoehn & Yahr I-III, MDS-UPDRS 67.62 ± 20.83), underwent physical activity based on dance movements (2x week for 6 months). Participants were assessed at baseline and after 6 months on movement (POMA, TUG and MDS-UPDRS Part III), executive function (FAB), depressive symptoms (MADRS), quality of life (PDQ-39), and severity of PD (MDS-UPDRS TOTAL). Student's t-test was used to compare pre and post-intervention results.
We observed a significant improvement in the movement (balance and gait) by the POMA test, p = 0.0207, executive function by the FAB test, p = 0.0074, abstract reasoning and inhibitory control by the FAB, Conceptualization test, p = 0.0062, and Inhibitory Control, p = 0.0064, depressive symptoms assessed by the MADRS test significantly reduced, p = 0.0214, and the quality of life by the PDQ-39 had a significant increase after the intervention, p = 0.0006, showed significant improvements between the pre-and post-intervention periods of physical activity based on dance movements.
Physical activity based on dance movements contributed to significant improvements in movement (balance and gait), executive functions, especially in cognitive flexibility and inhibitory control, and the quality of life too. Sensorimotor integration, most cognitive processing and social skills may have contributed to the results.
The study was registered in the Brazilian registry of clinical trials: RBR-3bhbrb5.
帕金森病（PD）是一种进行性神经退行性疾病，其运动症状得到了很好的理解，但非运动症状可能存在，并出现在疾病的不同时间阶段。基于舞蹈动作的身体活动作为一种多维活动，正在成为治疗一系列 PD 症状的补充治疗方法，这种活动需要节奏同步和更多的神经肌肉功能。
评估基于舞蹈动作的身体活动对诊断为 PD 的个体的运动、执行功能、抑郁症状、生活质量和 PD 严重程度的影响。
13 名 PD 患者（Hoehn & Yahr I-III，MDS-UPDRS 67.62 ± 20.83）接受了为期 6 个月的基于舞蹈动作的身体活动（每周 2 次）。参与者在基线和 6 个月后接受了运动（POMA、TUG 和 MDS-UPDRS 第 III 部分）、执行功能（FAB）、抑郁症状（MADRS）、生活质量（PDQ-39）和 PD 严重程度（MDS-UPDRS 总分）评估。采用学生 t 检验比较干预前后的结果。
我们观察到 POMA 测试中运动（平衡和步态）显著改善，p = 0.0207，FAB 测试中执行功能显著改善，p = 0.0074，FAB、概念化测试中抽象推理和抑制控制显著改善，p = 0.0062，和抑制控制，p = 0.0064，MADRS 测试评估的抑郁症状显著减轻，p = 0.0214，PDQ-39 评估的生活质量在干预后显著增加，p = 0.0006，表明基于舞蹈动作的身体活动在干预前后有显著改善。
基于舞蹈动作的身体活动有助于运动（平衡和步态）、执行功能，特别是认知灵活性和抑制控制，以及生活质量的显著改善。感觉运动整合、大多数认知加工和社交技能可能促成了这些结果。
该研究在巴西临床试验注册处注册：RBR-3bhbrb5。
