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自体或异体乳房重建术后 9 至 13 年的生活质量:哪种乳房保持最佳?

Quality of Life 9 to 13 Years after Autologous or Alloplastic Breast Reconstruction: Which Breast Remains Best?

机构信息

From the Departments of Plastic Surgery.

Epidemiology, University of Groningen, University Medical Center Groningen.

出版信息

Plast Reconstr Surg. 2023 Mar 1;151(3):467-476. doi: 10.1097/PRS.0000000000009899. Epub 2022 Nov 19.

Abstract

BACKGROUND

The aim of this study was to evaluate the long-term patient satisfaction and quality of life 9 to 13 years after autologous versus alloplastic breast reconstruction and compare the data to those of an earlier study.

METHODS

This is a 9-year follow-up study of 92 women who underwent breast reconstruction (47 autologous and 45 alloplastic) between 2006 and 2010 and filled out the BREAST-Q questionnaire in 2010. Changes in BREAST-Q scores were analyzed by using a change score from baseline (2010) to follow-up (2019), which was presented by a mean change score with 95% confidence intervals. Linear regression analyses were performed to test which patient characteristics were related to the BREAST-Q change scores.

RESULTS

The response rate at follow-up was 60% (25 autologous and 30 alloplastic). Responders at follow-up had a lower body mass index and had less frequently undergone unilateral breast reconstruction compared to the nonresponders. Women undergoing both autologous and alloplastic breast reconstruction had significantly decreased satisfaction with breasts (-4 points), satisfaction with outcome (-8 points), and satisfaction with nipples (-20 points) over time. None of the patient characteristics, including reconstruction technique, were related to the BREAST-Q change scores.

CONCLUSIONS

Satisfaction with breasts, satisfaction with outcome, and satisfaction with nipples decreased slightly over time for women undergoing alloplastic and autologous breast reconstruction. Women undergoing autologous breast reconstruction seemed to remain more satisfied with their breasts 9 to 13 years after breast reconstruction compared to women undergoing alloplastic breast reconstruction. Because of the small sample size, conclusions should be carefully drawn. However, the results were in line with the expectations based on previous literature.

摘要

背景

本研究旨在评估自体与假体乳房重建 9 至 13 年后的长期患者满意度和生活质量,并将数据与早期研究进行比较。

方法

这是一项对 92 名女性的 9 年随访研究,这些女性在 2006 年至 2010 年间接受了乳房重建(47 例自体,45 例假体),并在 2010 年填写了 BREAST-Q 问卷。通过使用从基线(2010 年)到随访(2019 年)的变化得分分析 BREAST-Q 评分的变化,以 95%置信区间的平均变化得分表示。进行线性回归分析以测试哪些患者特征与 BREAST-Q 变化得分相关。

结果

随访时的应答率为 60%(25 例自体,30 例假体)。与未应答者相比,随访时的应答者体重指数较低,且单侧乳房重建的频率较低。接受自体和假体乳房重建的女性随着时间的推移,对乳房的满意度(-4 分)、对结果的满意度(-8 分)和对乳头的满意度(-20 分)均显著下降。包括重建技术在内的任何患者特征均与 BREAST-Q 变化得分无关。

结论

接受自体和假体乳房重建的女性随着时间的推移,对乳房、结果和乳头的满意度略有下降。与接受假体乳房重建的女性相比,接受自体乳房重建的女性在乳房重建 9 至 13 年后似乎对乳房更满意。由于样本量较小,结论应谨慎得出。然而,这些结果与基于先前文献的预期相符。

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