Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY 10003, USA.
Curr Opin Ophthalmol. 2023 Mar 1;34(2):162-167. doi: 10.1097/ICU.0000000000000929. Epub 2022 Nov 9.
Choroidal effusions are recognized as a common early postoperative complication of glaucoma surgery, and although often benign, they may cause significant ocular morbidity. This article aims to summarize current research on the risk factors and management of choroidal effusions.
Glaucoma drainage device (GDD) implantation and trabeculectomy are the most commonly performed surgeries for the management of moderate to severe glaucoma. Common postoperative complications of these procedures include hypotony and the development of choroidal effusions. Choroidal effusions have recently been associated with the oral administration of certain drugs, including select monoclonal antibody, antiseizure and bisphosphonate medications. Risk factors for effusion development include specific patient characteristics such as pseudoexfoliative glaucoma, older age and hypertension. Although choroidal effusions typically resolve with medical therapy alone, surgical intervention may be required. Various methods of surgical intervention, such as surgical drainage or GDD tube ligation, can be utilized to treat choroidal effusions when conservative management with medical treatment fails, but themselves carry alternative risks that must be considered.
Minimizing the incidence and duration of hypotony following ophthalmic surgery and careful monitoring of patients starting certain oral medications are important in limiting the occurrence of choroidal effusions. Risk factors for choroidal effusions have been recently identified in the literature. A better understanding of these risk factors, as well as the outcomes of choroidal effusion management, can help to reduce the occurrence of effusions overall and minimize ocular morbidity.
脉络膜积液是青光眼手术后常见的早期并发症,虽然通常是良性的,但可能导致严重的眼部疾病。本文旨在总结脉络膜积液的风险因素和处理方法的最新研究进展。
青光眼引流装置(GDD)植入和小梁切除术是治疗中重度青光眼最常用的手术方法。这些手术的常见术后并发症包括低眼压和脉络膜积液的发生。脉络膜积液最近与某些药物的口服给药有关,包括某些单克隆抗体、抗癫痫药和双膦酸盐药物。积液发生的风险因素包括特定的患者特征,如假性剥脱性青光眼、年龄较大和高血压。尽管脉络膜积液通常可以单独通过药物治疗来解决,但可能需要手术干预。当药物治疗的保守管理失败时,可以使用各种手术干预方法(如手术引流或 GDD 管结扎)来治疗脉络膜积液,但这些方法本身会带来其他必须考虑的风险。
尽量减少眼科手术后低眼压的发生率和持续时间,并在开始使用某些口服药物时密切监测患者,这对于限制脉络膜积液的发生非常重要。脉络膜积液的风险因素最近在文献中得到了确认。更好地了解这些风险因素以及脉络膜积液处理的结果,可以帮助减少积液的总体发生率并最大限度地降低眼部疾病的发病率。